Amitrole, fipronil and triclosan reduce serum thyroxine and cause both unique and shared transcriptional effects in the hypothalamic-pituitary-thyroid axis and liver

L Ramhøj; N Davidsen; B Evrard; R Poulsen; I Strand; M Melchiors; M Axelstad; M Hansen; F Chalmel; T Svingen

Amitrole, fipronil and triclosan reduce serum thyroxine and cause both unique and shared transcriptional effects in the hypothalamic-pituitary-thyroid axis and liver

L Ramhøj^*
, N Davidsen
, B Evrard
, R Poulsen
, I Strand
, M Melchiors
, M Axelstad
, M Hansen
, F Chalmel
, T Svingen

^*Corresponding author for this work

Université de Rennes
Aarhus University

Research output: Contribution to conference › Poster › Research › peer-review

Abstract

Thyroid hormone (TH) system disrupting chemicals can act by many different mechanisms and may induce different effect profiles. Here, we aim to link low TH and unique apical effect profiles to molecular effects in the HPT-axis.

Original language	English
Publication date	2024
Number of pages	1
Publication status	Published - 2024
Event	Gordon Research Conference 2024: Environmental Endocrine Disruptors : Addressing Environmental Endocrine Disruptors to Improve Planetary Health - Renaissance Tuscany Il Ciocco, Lucca, Italy Duration: 23 Jun 2024 → 28 Jun 2024

Conference

Conference	Gordon Research Conference 2024: Environmental Endocrine Disruptors
Location	Renaissance Tuscany Il Ciocco
Country/Territory	Italy
City	Lucca
Period	23/06/2024 → 28/06/2024

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Ramhøj, L., Davidsen, N., Evrard, B., Poulsen, R., Strand, I., Melchiors, M., Axelstad, M., Hansen, M., Chalmel, F., & Svingen, T. (2024). Amitrole, fipronil and triclosan reduce serum thyroxine and cause both unique and shared transcriptional effects in the hypothalamic-pituitary-thyroid axis and liver. Poster session presented at Gordon Research Conference 2024: Environmental Endocrine Disruptors , Lucca, Italy.

@conference{b2a1e39226714f20932e051252b97124,

title = "Amitrole, fipronil and triclosan reduce serum thyroxine and cause both unique and shared transcriptional effects in the hypothalamic-pituitary-thyroid axis and liver",

abstract = "Thyroid hormone (TH) system disrupting chemicals can act by many different mechanisms and may induce different effect profiles. Here, we aim to link low TH and unique apical effect profiles to molecular effects in the HPT-axis.",

author = "L Ramh{\o}j and N Davidsen and B Evrard and R Poulsen and I Strand and M Melchiors and M Axelstad and M Hansen and F Chalmel and T Svingen",

year = "2024",

language = "English",

note = "Gordon Research Conference 2024: Environmental Endocrine Disruptors : Addressing Environmental Endocrine Disruptors to Improve Planetary Health, GRC 2024: Environmental Endocrine Disruptors ; Conference date: 23-06-2024 Through 28-06-2024",

}

Ramhøj, L, Davidsen, N, Evrard, B, Poulsen, R, Strand, I , Melchiors, M , Axelstad, M, Hansen, M, Chalmel, F & Svingen, T 2024, 'Amitrole, fipronil and triclosan reduce serum thyroxine and cause both unique and shared transcriptional effects in the hypothalamic-pituitary-thyroid axis and liver', Gordon Research Conference 2024: Environmental Endocrine Disruptors , Lucca, Italy, 23/06/2024 - 28/06/2024.

Amitrole, fipronil and triclosan reduce serum thyroxine and cause both unique and shared transcriptional effects in the hypothalamic-pituitary-thyroid axis and liver. / Ramhøj, L; Davidsen, N; Evrard, B et al.
2024. Poster session presented at Gordon Research Conference 2024: Environmental Endocrine Disruptors , Lucca, Italy.

Research output: Contribution to conference › Poster › Research › peer-review

TY - CONF

T1 - Amitrole, fipronil and triclosan reduce serum thyroxine and cause both unique and shared transcriptional effects in the hypothalamic-pituitary-thyroid axis and liver

AU - Ramhøj, L

AU - Davidsen, N

AU - Evrard, B

AU - Poulsen, R

AU - Strand, I

AU - Melchiors, M

AU - Axelstad, M

AU - Hansen, M

AU - Chalmel, F

AU - Svingen, T

PY - 2024

Y1 - 2024

N2 - Thyroid hormone (TH) system disrupting chemicals can act by many different mechanisms and may induce different effect profiles. Here, we aim to link low TH and unique apical effect profiles to molecular effects in the HPT-axis.

AB - Thyroid hormone (TH) system disrupting chemicals can act by many different mechanisms and may induce different effect profiles. Here, we aim to link low TH and unique apical effect profiles to molecular effects in the HPT-axis.

M3 - Poster

T2 - Gordon Research Conference 2024: Environmental Endocrine Disruptors

Y2 - 23 June 2024 through 28 June 2024

ER -

Amitrole, fipronil and triclosan reduce serum thyroxine and cause both unique and shared transcriptional effects in the hypothalamic-pituitary-thyroid axis and liver

Abstract

Conference

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