Altered vitamin D status in liver tissue and blood plasma from Greenland sledge dogs (Canis familiaris) dietary exposed to organohalogen contaminated minke whale (Balaenoptera acuterostrata) blubber

Christian Sonne, Maja Kirkegaard, Jette Jakobsen, Bjørn Munro Jenssen, Robert J. Letcher, Rune Dietz

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

This study compared vitamin D3 (vitD3) and 25-OH vitamin D3 (25OHD3) status in Greenland sledge dogs (Canis familiaris) given either minke whale (Balaenoptera acuterostrata) blubber high in organohalogen contaminants (OHCs) or clean porcine (Suis scrofa) fat for up to 636 days. A group of six exposed and six control sister bitches (maternal generation) and their three exposed and four control pups, respectively, were daily fed 112g whale blubber (193µg ∑PCB/day) or porcine fat (0.17µg ∑PCB/day). Mean level of ∑PCB in adipose tissue of exposed bitches and their pups was 3106 and 2670ng/g lw, respectively, which was significantly higher than the mean concentration of 53ng/g lw for all controls (p
Original languageEnglish
JournalEcotoxicology and Environmental Safety
Volume104
Pages (from-to)403-408
Number of pages6
ISSN0147-6513
DOIs
Publication statusPublished - 2014

Keywords

  • 25-Hydroxyvitamin D3
  • Sledge dogs
  • Organohalogen contaminants
  • PCBs
  • Polychlorinated biphenyls
  • Vitamin D3

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