Altered vitamin D status in liver tissue and blood plasma from Greenland sledge dogs (Canis familiaris) dietary exposed to organohalogen contaminated minke whale (Balaenoptera acuterostrata) blubber

Christian Sonne, Maja Kirkegaard, Jette Jakobsen, Bjørn Munro Jenssen, Robert J. Letcher, Rune Dietz

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

This study compared vitamin D3 (vitD3) and 25-OH vitamin D3 (25OHD3) status in Greenland sledge dogs (Canis familiaris) given either minke whale (Balaenoptera acuterostrata) blubber high in organohalogen contaminants (OHCs) or clean porcine (Suis scrofa) fat for up to 636 days. A group of six exposed and six control sister bitches (maternal generation) and their three exposed and four control pups, respectively, were daily fed 112g whale blubber (193µg ∑PCB/day) or porcine fat (0.17µg ∑PCB/day). Mean level of ∑PCB in adipose tissue of exposed bitches and their pups was 3106 and 2670ng/g lw, respectively, which was significantly higher than the mean concentration of 53ng/g lw for all controls (p
Original languageEnglish
JournalEcotoxicology and Environmental Safety
Volume104
Pages (from-to)403-408
Number of pages6
ISSN0147-6513
DOIs
Publication statusPublished - 2014

Keywords

  • 25-Hydroxyvitamin D3
  • Sledge dogs
  • Organohalogen contaminants
  • PCBs
  • Polychlorinated biphenyls
  • Vitamin D3

Cite this

@article{9ae06ab46e0d4a4180778bf29b92b8a0,
title = "Altered vitamin D status in liver tissue and blood plasma from Greenland sledge dogs (Canis familiaris) dietary exposed to organohalogen contaminated minke whale (Balaenoptera acuterostrata) blubber",
abstract = "This study compared vitamin D3 (vitD3) and 25-OH vitamin D3 (25OHD3) status in Greenland sledge dogs (Canis familiaris) given either minke whale (Balaenoptera acuterostrata) blubber high in organohalogen contaminants (OHCs) or clean porcine (Suis scrofa) fat for up to 636 days. A group of six exposed and six control sister bitches (maternal generation) and their three exposed and four control pups, respectively, were daily fed 112g whale blubber (193µg ∑PCB/day) or porcine fat (0.17µg ∑PCB/day). Mean level of ∑PCB in adipose tissue of exposed bitches and their pups was 3106 and 2670ng/g lw, respectively, which was significantly higher than the mean concentration of 53ng/g lw for all controls (p",
keywords = "25-Hydroxyvitamin D3, Sledge dogs, Organohalogen contaminants, PCBs, Polychlorinated biphenyls, Vitamin D3",
author = "Christian Sonne and Maja Kirkegaard and Jette Jakobsen and Jenssen, {Bj{\o}rn Munro} and Letcher, {Robert J.} and Rune Dietz",
year = "2014",
doi = "10.1016/j.ecoenv.2013.11.017",
language = "English",
volume = "104",
pages = "403--408",
journal = "Ecotoxicology and Environmental Safety",
issn = "0147-6513",
publisher = "Academic Press",

}

Altered vitamin D status in liver tissue and blood plasma from Greenland sledge dogs (Canis familiaris) dietary exposed to organohalogen contaminated minke whale (Balaenoptera acuterostrata) blubber. / Sonne, Christian; Kirkegaard, Maja; Jakobsen, Jette; Jenssen, Bjørn Munro; Letcher, Robert J.; Dietz, Rune.

In: Ecotoxicology and Environmental Safety, Vol. 104, 2014, p. 403-408.

Research output: Contribution to journalJournal articleResearchpeer-review

TY - JOUR

T1 - Altered vitamin D status in liver tissue and blood plasma from Greenland sledge dogs (Canis familiaris) dietary exposed to organohalogen contaminated minke whale (Balaenoptera acuterostrata) blubber

AU - Sonne, Christian

AU - Kirkegaard, Maja

AU - Jakobsen, Jette

AU - Jenssen, Bjørn Munro

AU - Letcher, Robert J.

AU - Dietz, Rune

PY - 2014

Y1 - 2014

N2 - This study compared vitamin D3 (vitD3) and 25-OH vitamin D3 (25OHD3) status in Greenland sledge dogs (Canis familiaris) given either minke whale (Balaenoptera acuterostrata) blubber high in organohalogen contaminants (OHCs) or clean porcine (Suis scrofa) fat for up to 636 days. A group of six exposed and six control sister bitches (maternal generation) and their three exposed and four control pups, respectively, were daily fed 112g whale blubber (193µg ∑PCB/day) or porcine fat (0.17µg ∑PCB/day). Mean level of ∑PCB in adipose tissue of exposed bitches and their pups was 3106 and 2670ng/g lw, respectively, which was significantly higher than the mean concentration of 53ng/g lw for all controls (p

AB - This study compared vitamin D3 (vitD3) and 25-OH vitamin D3 (25OHD3) status in Greenland sledge dogs (Canis familiaris) given either minke whale (Balaenoptera acuterostrata) blubber high in organohalogen contaminants (OHCs) or clean porcine (Suis scrofa) fat for up to 636 days. A group of six exposed and six control sister bitches (maternal generation) and their three exposed and four control pups, respectively, were daily fed 112g whale blubber (193µg ∑PCB/day) or porcine fat (0.17µg ∑PCB/day). Mean level of ∑PCB in adipose tissue of exposed bitches and their pups was 3106 and 2670ng/g lw, respectively, which was significantly higher than the mean concentration of 53ng/g lw for all controls (p

KW - 25-Hydroxyvitamin D3

KW - Sledge dogs

KW - Organohalogen contaminants

KW - PCBs

KW - Polychlorinated biphenyls

KW - Vitamin D3

U2 - 10.1016/j.ecoenv.2013.11.017

DO - 10.1016/j.ecoenv.2013.11.017

M3 - Journal article

VL - 104

SP - 403

EP - 408

JO - Ecotoxicology and Environmental Safety

JF - Ecotoxicology and Environmental Safety

SN - 0147-6513

ER -