Allergic contact dermatitis caused by cobalt in leather – clinical cases

David Bregnbak, Morten S. Opstrup, Morten Stendahl Jellesen, Jeanne D. Johansen, Jacob P. Thyssen

Research output: Contribution to journalJournal articleResearchpeer-review


In 2013, we raised suspicion that cobalt in leather could be responsible for hitherto unrecognized cases of allergic contact dermatitis. We saw a patient sensitized only to cobalt with clear long-term exposure to cobalt from a leather sofa, and observed resolution of dermatitis following avoidance [1]. In 2014, we performed a questionnaire study, which showed a positive and significant association between cobalt allergy and a history of dermatitis caused by non-occupational exposure to leather articles [2]. Recently, we published an article showing high amounts of cobalt in selected leather swatches from furniture [3]. Here, we report 2 additional cases of allergic cobalt dermatitis caused by consumer leather exposure, to increase awareness about this topic.
Original languageEnglish
JournalContact Dermatitis
Issue number6
Pages (from-to)366-368
Publication statusPublished - 2017


  • Allergic contact dermatitis
  • Allergy
  • Case report
  • Cobalt
  • Cobalt allergy
  • Cobalt chloride
  • Dermatitis
  • Leather
  • Metals
  • Sensitization
  • Spot test

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