Advances in the Process Development of Biocatalytic Processes

Pär Tufvesson, Joana Lima Ramos, Naweed Al-Haque, Krist Gernaey, John Woodley

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

Biocatalysis is already established in chemical synthesis on an industrial scale, in particular in the pharmaceutical sector. However, the wider implementation of biocatalysis is currently hindered by the extensive effort required to develop a competitive process. In order that resources spent on development are used in the most efficient manner for these challenging systems, a holistic view on process development and a more in-depth understanding of the underlying constraints (process related as well as biocatalyst related) are required. In this concept article a systematic approach to solve this problem is proposed, involving the use of process tools and methods to assist in development.
Original languageEnglish
JournalOrganic Process Research and Development
Volume17
Issue number10
Pages (from-to)1233-1238
ISSN1083-6160
DOIs
Publication statusPublished - 2013

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