Advanced wound care adhesives with improved moisture handling capabilities

Valeria Chiaula*, Piotr Mazurek, Anders Christian Nielsen, Anne Ladegaard Skov

*Corresponding author for this work

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

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Abstract

Broadly, for wounds to heal, a moist, clean and warm environment is required. A moist wound bed easily promotes growth factors and many cell types including epithelial cells to migrate, facilitating wound edge contraction. Thus, appropriate dressings play a significant role to create and maintain such environment. [1] Silicone adhesives are silicone elastomers which are not fully crosslinked but remain close to the gelation threshold (i.e. with a low crosslinking degree). [2, 3] Within the field of advanced wound care, silicone adhesives are currently the preferred, state-of-the-art adhesive system due to its gentle skin adhesion properties. However, due to their hydrophobic nature, current silicone adhesives for wound care face challenges when it comes to moisture handling. Here, we propose a novel, skin-friendly, industrially relevant glycerol-silicone hybrid adhesive with improved moisture handling due to the incorporation of emulsified glycerol. Various parameters will be taken into account in order to develop a relevant adhesive, in particular glycerol content, glycerol domain size and adhesive thickness to allow for a controlled moisture absorption. Additionally, we will show that required adhesive properties, such as peel adhesion and tackiness, are not compromised by the incorporation of emulsified glycerol.
Original languageEnglish
Publication date2019
Number of pages1
Publication statusPublished - 2019
Event2019 Science of Adhesion Conference GRC: Adhesion and Friction in Extreme Conditions and Translation to Practical Applications - Mount Holyoke College, South Hadley, United States
Duration: 21 Jul 201926 Jul 2019

Conference

Conference2019 Science of Adhesion Conference GRC
LocationMount Holyoke College
CountryUnited States
CitySouth Hadley
Period21/07/201926/07/2019

Cite this

Chiaula, V., Mazurek, P., Nielsen, A. C., & Skov, A. L. (2019). Advanced wound care adhesives with improved moisture handling capabilities. Abstract from 2019 Science of Adhesion Conference GRC, South Hadley, United States.
Chiaula, Valeria ; Mazurek, Piotr ; Nielsen, Anders Christian ; Skov, Anne Ladegaard. / Advanced wound care adhesives with improved moisture handling capabilities. Abstract from 2019 Science of Adhesion Conference GRC, South Hadley, United States.1 p.
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title = "Advanced wound care adhesives with improved moisture handling capabilities",
abstract = "Broadly, for wounds to heal, a moist, clean and warm environment is required. A moist wound bed easily promotes growth factors and many cell types including epithelial cells to migrate, facilitating wound edge contraction. Thus, appropriate dressings play a significant role to create and maintain such environment. [1] Silicone adhesives are silicone elastomers which are not fully crosslinked but remain close to the gelation threshold (i.e. with a low crosslinking degree). [2, 3] Within the field of advanced wound care, silicone adhesives are currently the preferred, state-of-the-art adhesive system due to its gentle skin adhesion properties. However, due to their hydrophobic nature, current silicone adhesives for wound care face challenges when it comes to moisture handling. Here, we propose a novel, skin-friendly, industrially relevant glycerol-silicone hybrid adhesive with improved moisture handling due to the incorporation of emulsified glycerol. Various parameters will be taken into account in order to develop a relevant adhesive, in particular glycerol content, glycerol domain size and adhesive thickness to allow for a controlled moisture absorption. Additionally, we will show that required adhesive properties, such as peel adhesion and tackiness, are not compromised by the incorporation of emulsified glycerol.",
author = "Valeria Chiaula and Piotr Mazurek and Nielsen, {Anders Christian} and Skov, {Anne Ladegaard}",
year = "2019",
language = "English",
note = "2019 Science of Adhesion Conference GRC : Adhesion and Friction in Extreme Conditions and Translation to Practical Applications ; Conference date: 21-07-2019 Through 26-07-2019",

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Chiaula, V, Mazurek, P, Nielsen, AC & Skov, AL 2019, 'Advanced wound care adhesives with improved moisture handling capabilities', 2019 Science of Adhesion Conference GRC, South Hadley, United States, 21/07/2019 - 26/07/2019.

Advanced wound care adhesives with improved moisture handling capabilities. / Chiaula, Valeria; Mazurek, Piotr; Nielsen, Anders Christian ; Skov, Anne Ladegaard.

2019. Abstract from 2019 Science of Adhesion Conference GRC, South Hadley, United States.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

TY - ABST

T1 - Advanced wound care adhesives with improved moisture handling capabilities

AU - Chiaula, Valeria

AU - Mazurek, Piotr

AU - Nielsen, Anders Christian

AU - Skov, Anne Ladegaard

PY - 2019

Y1 - 2019

N2 - Broadly, for wounds to heal, a moist, clean and warm environment is required. A moist wound bed easily promotes growth factors and many cell types including epithelial cells to migrate, facilitating wound edge contraction. Thus, appropriate dressings play a significant role to create and maintain such environment. [1] Silicone adhesives are silicone elastomers which are not fully crosslinked but remain close to the gelation threshold (i.e. with a low crosslinking degree). [2, 3] Within the field of advanced wound care, silicone adhesives are currently the preferred, state-of-the-art adhesive system due to its gentle skin adhesion properties. However, due to their hydrophobic nature, current silicone adhesives for wound care face challenges when it comes to moisture handling. Here, we propose a novel, skin-friendly, industrially relevant glycerol-silicone hybrid adhesive with improved moisture handling due to the incorporation of emulsified glycerol. Various parameters will be taken into account in order to develop a relevant adhesive, in particular glycerol content, glycerol domain size and adhesive thickness to allow for a controlled moisture absorption. Additionally, we will show that required adhesive properties, such as peel adhesion and tackiness, are not compromised by the incorporation of emulsified glycerol.

AB - Broadly, for wounds to heal, a moist, clean and warm environment is required. A moist wound bed easily promotes growth factors and many cell types including epithelial cells to migrate, facilitating wound edge contraction. Thus, appropriate dressings play a significant role to create and maintain such environment. [1] Silicone adhesives are silicone elastomers which are not fully crosslinked but remain close to the gelation threshold (i.e. with a low crosslinking degree). [2, 3] Within the field of advanced wound care, silicone adhesives are currently the preferred, state-of-the-art adhesive system due to its gentle skin adhesion properties. However, due to their hydrophobic nature, current silicone adhesives for wound care face challenges when it comes to moisture handling. Here, we propose a novel, skin-friendly, industrially relevant glycerol-silicone hybrid adhesive with improved moisture handling due to the incorporation of emulsified glycerol. Various parameters will be taken into account in order to develop a relevant adhesive, in particular glycerol content, glycerol domain size and adhesive thickness to allow for a controlled moisture absorption. Additionally, we will show that required adhesive properties, such as peel adhesion and tackiness, are not compromised by the incorporation of emulsified glycerol.

M3 - Conference abstract for conference

ER -

Chiaula V, Mazurek P, Nielsen AC, Skov AL. Advanced wound care adhesives with improved moisture handling capabilities. 2019. Abstract from 2019 Science of Adhesion Conference GRC, South Hadley, United States.