Abstract
Research on the structure of proteins can bring forth a wealth of information about biological function and can be
used to better understand the processes in living cells. This paper reports a new microfluidic sample preparation system
for the structural investigation of proteins by Small Angle X-ray Scattering (SAXS). The system includes hardware and
software features for precise fluidic control, synchrotron beamline control, UV absorbance measurements and automated
data analysis. The precise fluidic handling capabilities are used to transport and precisely position samples as small as
500 nL into the microfluidic chip’s detection chambers.
| Original language | English |
|---|---|
| Title of host publication | Proceedings of MicroTAS 2010 |
| Publication date | 2010 |
| ISBN (Print) | 978-0-9798064-3-8 |
| Publication status | Published - 2010 |
| Event | 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences - Groningen, Netherlands Duration: 3 Oct 2010 → 7 Oct 2010 Conference number: 14 https://microtasconferences.org/microtas2010/ |
Conference
| Conference | 14th International Conference on Miniaturized Systems for Chemistry and Life Sciences |
|---|---|
| Number | 14 |
| Country/Territory | Netherlands |
| City | Groningen |
| Period | 03/10/2010 → 07/10/2010 |
| Internet address |
Keywords
- Sample preparation
- Small Angle X-ray Scattering
- Two-phase flow
- Protein analysis