Acoustofluidics: theory and simulation of radiation forces at ultrasound resonances in microfluidic devices

Rune Barnkob, Henrik Bruus

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    Abstract

    Theoretical analysis is combined with numerical simulations to optimize designs and functionalities of acoustofluidic devices, i.e. microfluidic devices in which ultrasound waves are used to anipulate biological particles. The resonance frequencies and corresponding modes of the acoustic fields are calculated for various specific geometries of glass/silicon chips containing water-filled microchannels. A special emphasis is put on taking the surrounding glass/silicon material into account, thus going beyond the traditional transverse half-wavelength picture. For the resonance frequencies, where the largest possible acoustic powers are obtained in the microfluidic system, the time-averaged acoustic radiation force on single particles is determined. Schemes for in situ calibration of this force are presented and discussed.
    Original languageEnglish
    Title of host publicationProceedings of Meeting on Acoustics
    Volume6
    PublisherAcoustical Society of America
    Publication date2009
    DOIs
    Publication statusPublished - 2009
    Event157th Meeting of the Acoustical Society of America - Portland, Oregon, United States
    Duration: 18 May 200922 May 2009
    Conference number: 157

    Conference

    Conference157th Meeting of the Acoustical Society of America
    Number157
    CountryUnited States
    CityPortland, Oregon
    Period18/05/200922/05/2009

    Bibliographical note

    Copyright 2009. Acoustical Society of America. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the Acoustical Society of America.

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