Accurate study of FosPeg® distribution in a mouse model using fluorescence imaging technique and fluorescence white monte carlo simulations

Haiyan Xie, Haichun Liu, Pontus Svenmarker, Johan Axelsson, Susanna Gräfe, Jesper Holm Lundeman, Haynes Pak Hay Cheng, Maria Kyriazi, Niels Bendsoe, Peter E. Andersen, Katarina Svanberg, Stefan Andersson-Engels

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    Abstract

    Fluorescence imaging is used for quantitative in vivo assessment of drug concentration. Light attenuation in tissue is compensated for through Monte-Carlo simulations. The intrinsic fluorescence intensity, directly proportional to the drug concentration, could be obtained.
    Original languageEnglish
    JournalOptical Society of America. Journal B: Optical Physics
    Pages (from-to)BTuD6
    ISSN0740-3224
    Publication statusPublished - 2010
    EventOSA Biomedical Optics (BIOMED) Topical Meeting - Miami, United States
    Duration: 11 Apr 201014 Apr 2010

    Conference

    ConferenceOSA Biomedical Optics (BIOMED) Topical Meeting
    Country/TerritoryUnited States
    CityMiami
    Period11/04/201014/04/2010

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