Accurate study of FosPeg® distribution in a mouse model using fluorescence imaging technique and fluorescence white monte carlo simulations

Haiyan Xie, Haichun Liu, Pontus Svenmarker, Johan Axelsson, Susanna Gräfe, Jesper Holm Lundeman, Haynes Pak Hay Cheng, Maria Kyriazi, Niels Bendsoe, Peter E. Andersen, Katarina Svanberg, Stefan Andersson-Engels

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Abstract

Fluorescence imaging is used for quantitative in vivo assessment of drug concentration. Light attenuation in tissue is compensated for through Monte-Carlo simulations. The intrinsic fluorescence intensity, directly proportional to the drug concentration, could be obtained.
Original languageEnglish
JournalOptical Society of America. Journal B: Optical Physics
Pages (from-to)BTuD6
ISSN0740-3224
Publication statusPublished - 2010
EventOSA Biomedical Optics (BIOMED) Topical Meeting - Miami, United States
Duration: 11 Apr 201014 Apr 2010

Conference

ConferenceOSA Biomedical Optics (BIOMED) Topical Meeting
CountryUnited States
CityMiami
Period11/04/201014/04/2010

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