Absence of strictly age-related resistance to Mycoplasma hyosynoviae infection in 6-week-old pigs

Klara Tølbøll Lauritsen, Tine Hagedorn-Olsen, Niels Filskov Friis, Peter Lind, Gregers Jungersen

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    Abstract

    Mycoplasma hyosynoviae has never been reported to cause arthritis in pigs younger than 10 weeks of age. In order to investigate whether a strict age-related resistance exists, four 6-week-old pigs and four 13-week-old pigs, all immunologically naïve with respect to M. hyosynoviae, were inoculated intranasally with the agent and autopsied at day 11 or 13 after infection. One uninoculated pig per age group was included as a negative control. Just as the 13-week-old pigs, the 6-week-old piglets were susceptible to blood, joint and tonsillar infection with M. hyosynoviae and developed clinical arthritis following inoculation with the agent. Thus, we found no evidence of an age-related resistance to the infection.
    Original languageEnglish
    JournalVeterinary Microbiology
    Volume130
    Issue number3-4
    Pages (from-to)385-390
    ISSN0378-1135
    DOIs
    Publication statusPublished - 2008

    Cite this

    Lauritsen, K. T., Hagedorn-Olsen, T., Filskov Friis, N., Lind, P., & Jungersen, G. (2008). Absence of strictly age-related resistance to Mycoplasma hyosynoviae infection in 6-week-old pigs. Veterinary Microbiology, 130(3-4), 385-390. https://doi.org/10.1016/j.vetmic.2008.02.002