Absence of strictly age-related resistance to Mycoplasma hyosynoviae infection in 6-week-old pigs

Klara Tølbøll Lauritsen; Tine Hagedorn-Olsen; Niels Filskov Friis; Peter Lind; Gregers Jungersen

doi:10.1016/j.vetmic.2008.02.002

Absence of strictly age-related resistance to Mycoplasma hyosynoviae infection in 6-week-old pigs

Klara Tølbøll Lauritsen, Tine Hagedorn-Olsen, Niels Filskov Friis, Peter Lind, Gregers Jungersen

Research output: Contribution to journal › Journal article › Research › peer-review

Abstract

Mycoplasma hyosynoviae has never been reported to cause arthritis in pigs younger than 10 weeks of age. In order to investigate whether a strict age-related resistance exists, four 6-week-old pigs and four 13-week-old pigs, all immunologically naïve with respect to M. hyosynoviae, were inoculated intranasally with the agent and autopsied at day 11 or 13 after infection. One uninoculated pig per age group was included as a negative control. Just as the 13-week-old pigs, the 6-week-old piglets were susceptible to blood, joint and tonsillar infection with M. hyosynoviae and developed clinical arthritis following inoculation with the agent. Thus, we found no evidence of an age-related resistance to the infection.

Original language	English
Journal	Veterinary Microbiology
Volume	130
Issue number	3-4
Pages (from-to)	385-390
ISSN	0378-1135
DOIs	https://doi.org/10.1016/j.vetmic.2008.02.002
Publication status	Published - 2008

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10.1016/j.vetmic.2008.02.002

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Lauritsen, K. T., Hagedorn-Olsen, T., Filskov Friis, N., Lind, P., & Jungersen, G. (2008). Absence of strictly age-related resistance to Mycoplasma hyosynoviae infection in 6-week-old pigs. Veterinary Microbiology, 130(3-4), 385-390. https://doi.org/10.1016/j.vetmic.2008.02.002

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title = "Absence of strictly age-related resistance to Mycoplasma hyosynoviae infection in 6-week-old pigs",

abstract = "Mycoplasma hyosynoviae has never been reported to cause arthritis in pigs younger than 10 weeks of age. In order to investigate whether a strict age-related resistance exists, four 6-week-old pigs and four 13-week-old pigs, all immunologically na{\"i}ve with respect to M. hyosynoviae, were inoculated intranasally with the agent and autopsied at day 11 or 13 after infection. One uninoculated pig per age group was included as a negative control. Just as the 13-week-old pigs, the 6-week-old piglets were susceptible to blood, joint and tonsillar infection with M. hyosynoviae and developed clinical arthritis following inoculation with the agent. Thus, we found no evidence of an age-related resistance to the infection.",

author = "Lauritsen, {Klara T{\o}lb{\o}ll} and Tine Hagedorn-Olsen and {Filskov Friis}, Niels and Peter Lind and Gregers Jungersen",

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T1 - Absence of strictly age-related resistance to Mycoplasma hyosynoviae infection in 6-week-old pigs

AU - Lauritsen, Klara Tølbøll

AU - Hagedorn-Olsen, Tine

AU - Filskov Friis, Niels

AU - Lind, Peter

AU - Jungersen, Gregers

PY - 2008

Y1 - 2008

N2 - Mycoplasma hyosynoviae has never been reported to cause arthritis in pigs younger than 10 weeks of age. In order to investigate whether a strict age-related resistance exists, four 6-week-old pigs and four 13-week-old pigs, all immunologically naïve with respect to M. hyosynoviae, were inoculated intranasally with the agent and autopsied at day 11 or 13 after infection. One uninoculated pig per age group was included as a negative control. Just as the 13-week-old pigs, the 6-week-old piglets were susceptible to blood, joint and tonsillar infection with M. hyosynoviae and developed clinical arthritis following inoculation with the agent. Thus, we found no evidence of an age-related resistance to the infection.

AB - Mycoplasma hyosynoviae has never been reported to cause arthritis in pigs younger than 10 weeks of age. In order to investigate whether a strict age-related resistance exists, four 6-week-old pigs and four 13-week-old pigs, all immunologically naïve with respect to M. hyosynoviae, were inoculated intranasally with the agent and autopsied at day 11 or 13 after infection. One uninoculated pig per age group was included as a negative control. Just as the 13-week-old pigs, the 6-week-old piglets were susceptible to blood, joint and tonsillar infection with M. hyosynoviae and developed clinical arthritis following inoculation with the agent. Thus, we found no evidence of an age-related resistance to the infection.

U2 - 10.1016/j.vetmic.2008.02.002

DO - 10.1016/j.vetmic.2008.02.002

M3 - Journal article

C2 - 18534787

VL - 130

SP - 385

EP - 390

JO - Veterinary Microbiology

JF - Veterinary Microbiology

SN - 0378-1135

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