A Unifying model of perfusion and motion applied to reconstruction of sparsely sampled free-breathing myocardial perfusion MRI

Henrik Pedersen, Hildur Ólafsdóttir, Rasmus Larsen, Henrik B. W. Larsson

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

    Abstract

    The clinical potential of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is currently limited by respiratory induced motion of the heart. This paper presents a unifying model of perfusion and motion in which respiratory motion becomes an integral part of myocardial perfusion quantification. Hence, the need for tedious manual motion correction prior to perfusion quantification is avoided. In addition, we demonstrate that the proposed framework facilitates the process of reconstructing DCEMRI from sparsely sampled data in the presence of respiratory motion. The paper focuses primarily on the underlying theory of the proposed framework, but shows in vivo results of respiratory motion correction and simulation results of reconstructing sparsely sampled data.
    Original languageEnglish
    Title of host publicationProceedings of IEEE International Symposium on Biomedical Imaging : From Nano to Macro
    PublisherIEEE
    Publication date2010
    Pages752-755
    ISBN (Print)978-1-4244-4125-9
    DOIs
    Publication statusPublished - 2010
    Event2010 IEEE International Symposium on Biomedical Imaging: From Nano to Macro - Rotterdam, Netherlands
    Duration: 14 Apr 201017 Apr 2010
    Conference number: 7
    http://ieeexplore.ieee.org/xpl/mostRecentIssue.jsp?punumber=5481762

    Conference

    Conference2010 IEEE International Symposium on Biomedical Imaging
    Number7
    Country/TerritoryNetherlands
    CityRotterdam
    Period14/04/201017/04/2010
    Internet address

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