TY - JOUR
T1 - A surface-modified graphene–carbon-based composite sensor for the voltammetric assessment of pyridoxine in food and pharmaceutical samples
AU - Battira Madappa, Sharmila
AU - Manjunatha, Jamballi Gangadarappa
AU - Karnayana, Moulya
AU - Mahmoud Osman, Sameh
AU - Patra, Santanu
N1 - Publisher Copyright:
© 2024 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.
PY - 2024
Y1 - 2024
N2 - A novel poly (glutamic acid)-modified graphene carbon paste sensor (PGMGCPS) was developed by the electro-polymerization technique for the analysis of Pyridoxine (PYX). Scanning electron microscopy (SEM), X-ray diffraction (XRD), Energy dispersive X-ray (EDX) and Electrochemical impedance spectroscopy (EIS) were employed to gain a deep insight into the surface modification and elemental analysis of the unmodified graphene carbon paste sensor (UGCPS) and PGMGCPS. The study of the impact of scan rate on the PYX analysis at the PGMGCPS surface revealed that the oxidation process is diffusion-controlled and at an optimum pH of 6.0 of PBS (phosphate buffer solution, 0.2 M), the sensor demonstrated a detection limit (DL) of 0.09 × 10−7 M and 0.35 × 10−6 M through CV and DPV methods, respectively. A probe into the crucial attributes like repeatability, reproducibility, stability and concurrent analysing capacity signified the designed sensor as an efficient electrochemical tool to analyse PYX in food and pharmaceutical samples.
AB - A novel poly (glutamic acid)-modified graphene carbon paste sensor (PGMGCPS) was developed by the electro-polymerization technique for the analysis of Pyridoxine (PYX). Scanning electron microscopy (SEM), X-ray diffraction (XRD), Energy dispersive X-ray (EDX) and Electrochemical impedance spectroscopy (EIS) were employed to gain a deep insight into the surface modification and elemental analysis of the unmodified graphene carbon paste sensor (UGCPS) and PGMGCPS. The study of the impact of scan rate on the PYX analysis at the PGMGCPS surface revealed that the oxidation process is diffusion-controlled and at an optimum pH of 6.0 of PBS (phosphate buffer solution, 0.2 M), the sensor demonstrated a detection limit (DL) of 0.09 × 10−7 M and 0.35 × 10−6 M through CV and DPV methods, respectively. A probe into the crucial attributes like repeatability, reproducibility, stability and concurrent analysing capacity signified the designed sensor as an efficient electrochemical tool to analyse PYX in food and pharmaceutical samples.
KW - Carbon paste electrode (CPE)
KW - Cyclic voltammetry
KW - Differential pulse voltammetry
KW - Glutamic acid (GA)
KW - Graphene paste electrode (GPE)
KW - Pyridoxine
U2 - 10.1080/16583655.2024.2359209
DO - 10.1080/16583655.2024.2359209
M3 - Journal article
AN - SCOPUS:85195139636
SN - 1658-3655
VL - 18
JO - Journal of Taibah University for Science
JF - Journal of Taibah University for Science
IS - 1
M1 - 2359209
ER -