TY - JOUR
T1 - A support structure for biomimetic applications
AU - Vogel, Jörg
AU - Perry, Mark
AU - Hansen, Jesper Søndergaard
AU - Pierre-Yves, Bolinger
AU - Helix Nielsen, Claus
AU - Geschke, Oliver
PY - 2009
Y1 - 2009
N2 - Water filtration on the basis of aquaporin molecules incorporated in an artificial lipid bilayer requires a microporous support membrane. We describe a new microfabrication method based on CO2-laser ablation to generate support membranes with homogeneous apertures ranging from 300 mu m down to 84 mu m in diameter. They are arranged in arrays with the densest packaging having a perforation level of up to 60%. The apertures are surrounded by a smooth bulge that is formed by melted material ejected from the aperture during laser ablation. Polydimethylsiloxane (PDMS) replicas were used to visualize and analyse these bulges. The overall area covered so far has been 4 cm(2) but upscaling to larger footprints, e. g. square metres, is currently being investigated.
AB - Water filtration on the basis of aquaporin molecules incorporated in an artificial lipid bilayer requires a microporous support membrane. We describe a new microfabrication method based on CO2-laser ablation to generate support membranes with homogeneous apertures ranging from 300 mu m down to 84 mu m in diameter. They are arranged in arrays with the densest packaging having a perforation level of up to 60%. The apertures are surrounded by a smooth bulge that is formed by melted material ejected from the aperture during laser ablation. Polydimethylsiloxane (PDMS) replicas were used to visualize and analyse these bulges. The overall area covered so far has been 4 cm(2) but upscaling to larger footprints, e. g. square metres, is currently being investigated.
U2 - 10.1088/0960-1317/19/2/025026
DO - 10.1088/0960-1317/19/2/025026
M3 - Journal article
VL - 19
SP - 025026
JO - Journal of Micromechanics and Microengineering
JF - Journal of Micromechanics and Microengineering
SN - 0960-1317
IS - 2
ER -