Abstract
Auger electron therapy is an attractive modality for targeting microscopic tumors. Rhodium-103 m (103mRh, T½ = 56.1 min) is a promising Auger electron emitter that can be obtained as the decay product of palladium-103 (103Pd, T½ = 16.99 days). 103Pd was chelated in a lipophilic derivative of the 16aneS4 macrocycle and the complex was trapped on a C18 cartridge. Elution with dilute hydrochloric acid gave radiochemically pure 103mRh. We hypothesize this to be through a combination of the Szilard-Chalmers effect and transient ionization.
Original language | English |
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Article number | 108985 |
Journal | Applied Radiation and Isotopes |
Volume | 156 |
Number of pages | 7 |
ISSN | 0969-8043 |
DOIs | |
Publication status | Published - 2020 |
Keywords
- Auger radiotherapy
- Radionuclide generator
- Rhodium-103m
- Palladium-103
- 16aneS4