A Simple Hydrophilic Treatment of SU-8 Surfaces for Cell Culturing and Cell Patterning

Zhenyu Wang; Michael Stangegaard; Hans Martin Dufva; Jörg Peter Kutter; Anders Wolff

A Simple Hydrophilic Treatment of SU-8 Surfaces for Cell Culturing and Cell Patterning

Zhenyu Wang
, Michael Stangegaard
, Hans Martin Dufva
, Jörg Peter Kutter
, Anders Wolff

Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

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Abstract

SU-8, an epoxy-based photoresist, widely used in constitution different μTAS systems, is incompatible with mammalian cell adhesion and culture in its native form. Here, we demonstrate a simple, cheap and robust two-step method to render a SU-8 surface hydrophilic and compatible with cell culture. The contact angle of SU-8 surface was significantly reduced from 90° to 25° after the surface modification. The treated SU-8 surfaces provided a cell culture environment that was comparable with cell culture flask surface in terms of generation time and morphology.

Original language	English
Title of host publication	Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Volume	1
Publication date	2005
Pages	745-747
ISBN (Print)	978-097436111-6
Publication status	Published - 2005
Event	9th International Conference on Miniaturized Systems for Chemistry and Life Sciences - Boston Marriott Copley Place, Boston, United States Duration: 9 Oct 2005 → 13 Oct 2005 Conference number: 9 https://microtasconferences.org/microtas2005/ http://www.microtasconferences.org/microtas2005/

Conference

Conference	9th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Number	9
Location	Boston Marriott Copley Place
Country/Territory	United States
City	Boston
Period	09/10/2005 → 13/10/2005
Internet address	https://microtasconferences.org/microtas2005/ http://www.microtasconferences.org/microtas2005/

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@inproceedings{658b09e65ffc488b9510f9f9bb78f19b,

title = "A Simple Hydrophilic Treatment of SU-8 Surfaces for Cell Culturing and Cell Patterning",

abstract = "SU-8, an epoxy-based photoresist, widely used in constitution different μTAS systems, is incompatible with mammalian cell adhesion and culture in its native form. Here, we demonstrate a simple, cheap and robust two-step method to render a SU-8 surface hydrophilic and compatible with cell culture. The contact angle of SU-8 surface was significantly reduced from 90° to 25° after the surface modification. The treated SU-8 surfaces provided a cell culture environment that was comparable with cell culture flask surface in terms of generation time and morphology.",

author = "Zhenyu Wang and Michael Stangegaard and Dufva, \{Hans Martin\} and Kutter, \{J{\"o}rg Peter\} and Anders Wolff",

year = "2005",

language = "English",

isbn = "978-097436111-6",

volume = "1",

pages = "745--747",

booktitle = "Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences",

note = "9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2005 ; Conference date: 09-10-2005 Through 13-10-2005",

url = "https://microtasconferences.org/microtas2005/, http://www.microtasconferences.org/microtas2005/",

}

Wang, Z, Stangegaard, M, Dufva, HM, Kutter, JP & Wolff, A 2005, A Simple Hydrophilic Treatment of SU-8 Surfaces for Cell Culturing and Cell Patterning. in Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences. vol. 1, pp. 745-747, 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Boston, Massachusetts, United States, 09/10/2005.

A Simple Hydrophilic Treatment of SU-8 Surfaces for Cell Culturing and Cell Patterning. / Wang, Zhenyu; Stangegaard, Michael; Dufva, Hans Martin et al.
Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Vol. 1 2005. p. 745-747.

Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

TY - GEN

T1 - A Simple Hydrophilic Treatment of SU-8 Surfaces for Cell Culturing and Cell Patterning

AU - Wang, Zhenyu

AU - Stangegaard, Michael

AU - Dufva, Hans Martin

AU - Kutter, Jörg Peter

AU - Wolff, Anders

N1 - Conference code: 9

PY - 2005

Y1 - 2005

N2 - SU-8, an epoxy-based photoresist, widely used in constitution different μTAS systems, is incompatible with mammalian cell adhesion and culture in its native form. Here, we demonstrate a simple, cheap and robust two-step method to render a SU-8 surface hydrophilic and compatible with cell culture. The contact angle of SU-8 surface was significantly reduced from 90° to 25° after the surface modification. The treated SU-8 surfaces provided a cell culture environment that was comparable with cell culture flask surface in terms of generation time and morphology.

AB - SU-8, an epoxy-based photoresist, widely used in constitution different μTAS systems, is incompatible with mammalian cell adhesion and culture in its native form. Here, we demonstrate a simple, cheap and robust two-step method to render a SU-8 surface hydrophilic and compatible with cell culture. The contact angle of SU-8 surface was significantly reduced from 90° to 25° after the surface modification. The treated SU-8 surfaces provided a cell culture environment that was comparable with cell culture flask surface in terms of generation time and morphology.

M3 - Article in proceedings

SN - 978-097436111-6

VL - 1

SP - 745

EP - 747

BT - Micro Total Analysis Systems - Proceedings of MicroTAS 2005 Conference: 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences

T2 - 9th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Y2 - 9 October 2005 through 13 October 2005

ER -

A Simple Hydrophilic Treatment of SU-8 Surfaces for Cell Culturing and Cell Patterning

Abstract

Conference

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