A retrofit strategy to achieve “Fast, Flexible, Future (F3)” pharmaceutical production processes

Ravendra Singh; Raquel Rozada-Sanchez; Tim Wrate; Frans Muller; Krist Gernaey; Rafiqul Gani; John Woodley

doi:10.1016/B978-0-444-53711-9.50059-6

A retrofit strategy to achieve “Fast, Flexible, Future (F3)” pharmaceutical production processes

Ravendra Singh
, Raquel Rozada-Sanchez
, Tim Wrate
, Frans Muller
, Krist Gernaey
, Rafiqul Gani
, John Woodley

Department of Chemical and Biochemical Engineering

AstraZeneca

Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

Abstract

n the work reported here, a substrates adoption methodology for a series of similar substrates has been developed as part of a retrofit strategy. The objective is to achieve “fast, flexible and future” pharmaceutical production processes by adapting a generic modular process-plant template. Application of the methodology is illustrated through a case study from the pharmaceutical industry. Use of computer-aided models, methods and tools as part of the methodology is also highlighted.

Original language	English
Title of host publication	21st European Symposium on Computer Aided Process Engineering
Number of pages	2029
Publisher	Elsevier
Publication date	2011
Pages	291-295
ISBN (Print)	978-0-444-53895-6
DOIs	https://doi.org/10.1016/B978-0-444-53711-9.50059-6
Publication status	Published - 2011
Event	21st European Symposium on Computer Aided Process Engineering - Chalkidiki, Greece Duration: 29 May 2011 → 1 Jun 2011 http://www.escape-21.gr/

Conference

Conference	21st European Symposium on Computer Aided Process Engineering
Country/Territory	Greece
City	Chalkidiki
Period	29/05/2011 → 01/06/2011
Internet address	http://www.escape-21.gr/

Series	Computer Aided Chemical Engineering
Number	29
ISSN	1570-7946

Keywords

Fast
Retrofit strategy
Substrates adoption methodology
Flexible

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title = "A retrofit strategy to achieve “Fast, Flexible, Future (F3)” pharmaceutical production processes",

abstract = "n the work reported here, a substrates adoption methodology for a series of similar substrates has been developed as part of a retrofit strategy. The objective is to achieve “fast, flexible and future” pharmaceutical production processes by adapting a generic modular process-plant template. Application of the methodology is illustrated through a case study from the pharmaceutical industry. Use of computer-aided models, methods and tools as part of the methodology is also highlighted.",

keywords = "Fast, Retrofit strategy, Substrates adoption methodology, Flexible",

author = "Ravendra Singh and Raquel Rozada-Sanchez and Tim Wrate and Frans Muller and Krist Gernaey and Rafiqul Gani and John Woodley",

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language = "English",

isbn = "978-0-444-53895-6",

series = "Computer Aided Chemical Engineering",

publisher = "Elsevier",

number = "29",

pages = "291--295",

booktitle = "21st European Symposium on Computer Aided Process Engineering",

address = "United Kingdom",

note = "21st European Symposium on Computer Aided Process Engineering, ESCAPE 21 ; Conference date: 29-05-2011 Through 01-06-2011",

url = "http://www.escape-21.gr/",

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Singh, R, Rozada-Sanchez, R, Wrate, T, Muller, F, Gernaey, K, Gani, R & Woodley, J 2011, A retrofit strategy to achieve “Fast, Flexible, Future (F3)” pharmaceutical production processes. in 21st European Symposium on Computer Aided Process Engineering. Elsevier, Computer Aided Chemical Engineering, no. 29, pp. 291-295, 21st European Symposium on Computer Aided Process Engineering, Chalkidiki, Greece, 29/05/2011. https://doi.org/10.1016/B978-0-444-53711-9.50059-6

A retrofit strategy to achieve “Fast, Flexible, Future (F3)” pharmaceutical production processes. / Singh, Ravendra; Rozada-Sanchez, Raquel; Wrate, Tim et al.
21st European Symposium on Computer Aided Process Engineering. Elsevier, 2011. p. 291-295 (Computer Aided Chemical Engineering; No. 29).

Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

TY - GEN

T1 - A retrofit strategy to achieve “Fast, Flexible, Future (F3)” pharmaceutical production processes

AU - Singh, Ravendra

AU - Rozada-Sanchez, Raquel

AU - Wrate, Tim

AU - Muller, Frans

AU - Gernaey, Krist

AU - Gani, Rafiqul

AU - Woodley, John

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N2 - n the work reported here, a substrates adoption methodology for a series of similar substrates has been developed as part of a retrofit strategy. The objective is to achieve “fast, flexible and future” pharmaceutical production processes by adapting a generic modular process-plant template. Application of the methodology is illustrated through a case study from the pharmaceutical industry. Use of computer-aided models, methods and tools as part of the methodology is also highlighted.

AB - n the work reported here, a substrates adoption methodology for a series of similar substrates has been developed as part of a retrofit strategy. The objective is to achieve “fast, flexible and future” pharmaceutical production processes by adapting a generic modular process-plant template. Application of the methodology is illustrated through a case study from the pharmaceutical industry. Use of computer-aided models, methods and tools as part of the methodology is also highlighted.

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KW - Retrofit strategy

KW - Substrates adoption methodology

KW - Flexible

U2 - 10.1016/B978-0-444-53711-9.50059-6

DO - 10.1016/B978-0-444-53711-9.50059-6

M3 - Article in proceedings

SN - 978-0-444-53895-6

T3 - Computer Aided Chemical Engineering

SP - 291

EP - 295

BT - 21st European Symposium on Computer Aided Process Engineering

PB - Elsevier

T2 - 21st European Symposium on Computer Aided Process Engineering

Y2 - 29 May 2011 through 1 June 2011

ER -

A retrofit strategy to achieve “Fast, Flexible, Future (F3)” pharmaceutical production processes

Abstract

Conference

Keywords

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