TY - JOUR
T1 - A prospective analysis of the association between macronutrient intake and renal cell carcinoma in the European Prospective Investigation into Cancer and Nutrition
AU - Allen, Naomi E.
AU - Roddam, Andrew W.
AU - Sieri, Sabina
AU - Boeing, Heiner
AU - Jakobsen, Marianne Uhre
AU - Overvad, Kim
AU - Tjonneland, Anne
AU - Halkjaer, Jytte
AU - Vineis, Paolo
AU - Contiero, Paolo
AU - Palli, Domenico
AU - Tumino, Rosario
AU - Mattiello, Amalia
AU - Kaaks, Rudolf
AU - Rohrmann, Sabine
AU - Trichopoulou, Antonia
AU - Zilis, Demosthenes
AU - Koumantaki, Yvoni
AU - Peeters, Petra H.
AU - Bueno-de-Mesquita, H. Bas
AU - Barricarte, Aurelio
AU - Rodriguez, Laudina
AU - Dorronsoro, Miren
AU - Sanchez, Maria-Jose
AU - Dolores Chirlaque, Maria
AU - Esquius, Laura
AU - Manjer, Jonas
AU - Wallstrom, Peter
AU - Ljungberg, Borje
AU - Hallmans, Goran
AU - Bingham, Sheila
AU - Khaw, Kay-Tee
AU - Boffetta, Paolo
AU - Norat, Teresa
AU - Mouw, Traci
AU - Riboli, Elio
PY - 2009
Y1 - 2009
N2 - Previous case-control studies have suggested that a high intake of animal foods and its associated nutrients are associated with an increased risk of renal cell carcinoma, although data from prospective studies are limited. We report here on the relationship between macronutrient intake and renal cell carcinoma incidence among 435,293 participants enrolled in the European Prospective Investigation into Cancer and Nutrition. Cox proportional hazard models were used to examine the association of dietary intake of fat, protein, carbohydrate, fiber and cholesterol and risk of renal cell carcinoma adjusted for age, sex, center, height, body mass index, physical activity, education, smoking, menopausal status, alcohol and energy intake. During an average 8.8 years of follow-up, 507 renal cell carcinoma cases occurred. Risk of renal cell carcinoma was not associated with macronutrient intake, including nutrients derived from animal sources. Our results indicate that macronutrient intake is not associated with risk of renal cell carcinoma in this cohort of European men and women.
AB - Previous case-control studies have suggested that a high intake of animal foods and its associated nutrients are associated with an increased risk of renal cell carcinoma, although data from prospective studies are limited. We report here on the relationship between macronutrient intake and renal cell carcinoma incidence among 435,293 participants enrolled in the European Prospective Investigation into Cancer and Nutrition. Cox proportional hazard models were used to examine the association of dietary intake of fat, protein, carbohydrate, fiber and cholesterol and risk of renal cell carcinoma adjusted for age, sex, center, height, body mass index, physical activity, education, smoking, menopausal status, alcohol and energy intake. During an average 8.8 years of follow-up, 507 renal cell carcinoma cases occurred. Risk of renal cell carcinoma was not associated with macronutrient intake, including nutrients derived from animal sources. Our results indicate that macronutrient intake is not associated with risk of renal cell carcinoma in this cohort of European men and women.
KW - Diet
KW - EPIC
KW - Macronutrients
KW - Prospective
KW - Renal cell carcinoma
U2 - 10.1002/ijc.24447
DO - 10.1002/ijc.24447
M3 - Journal article
SN - 0020-7136
VL - 125
SP - 982
EP - 987
JO - International Journal of Cancer
JF - International Journal of Cancer
IS - 4
ER -
