A novel in silico phantom for microstructure, tractography and quantitative connectivity estimation

Gabriel Girard, Jonathan Rafael-Patino, Raphaël Truffet, Marco Pizzolato, Emmanuel Caruyer, Jean-Philippe Thiran

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Abstract

In this work, we propose a novel phantom obtained from Monte-Carlo simulations of spins dynamics to improve testing and validation of DW-MRI quantitative structural connectivity. The DiSCo (Diffusion-Simulated Connectivity) phantom is composed of 16 regions of interest placed on a sphere of 1 millimeter in diameter, interconnected by 12,196 axon-like tubular fibers ranging from 1.4um to 4.2um in diameter. Its associated connectivity matrix is weighted by their cross-sectional areas. This in silico phantom, with both microscopic and macroscopic complexity, aims at improving the development and the validation of white matter connectivity estimation methods.
Original languageEnglish
Publication date2021
Number of pages3
Publication statusPublished - 2021
Event2021 ISMRM & SMRT Annual Meeting & Exhibition - Online
Duration: 15 May 202120 May 2021

Conference

Conference2021 ISMRM & SMRT Annual Meeting & Exhibition
LocationOnline
Period15/05/202120/05/2021

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