A novel gold nanoparticle-DNA aptamer-based plasmonic chip for rapid and sensitive detection of bacterial pathogens

Yi Sun; Truong Phuoc Long; Anders Wolff; Dang Duong Bang

A novel gold nanoparticle-DNA aptamer-based plasmonic chip for rapid and sensitive detection of bacterial pathogens

Yi Sun
, Truong Phuoc Long
, Anders Wolff
, Dang Duong Bang

National Food Institute

Research output: Chapter in Book/Report/Conference proceeding › Conference abstract in proceedings › Research › peer-review

Abstract

Gold nanoparticles (AuNPs)-based biosensors are emerging technologies for rapid detection of pathogens. However, it is very challenging to develop chip-based AuNP-biosensors for whole cells. This paper describes a novel AuNPs-DNA aptamer-based plasmonic assay which allows DNA aptamers to be detached from AuNPs when interacting with bacteria. The new strategy greatly increases the sensitivity and specificity of chip-based whole-cell biosensing.

Original language	English
Title of host publication	20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
Number of pages	2
Publisher	Chemical and Biological Microsystems Society
Publication date	2016
Pages	1222-1223
Publication status	Published - 2016
Event	20th International Conference on Miniaturized Systems for Chemistry and Life Sciences - Convention Center Dublin, Dublin, Ireland Duration: 9 Oct 2016 → 13 Oct 2016 Conference number: 20 https://microtasconferences.org/microtas2016/

Conference

Conference	20th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Number	20
Location	Convention Center Dublin
Country/Territory	Ireland
City	Dublin
Period	09/10/2016 → 13/10/2016
Internet address	https://microtasconferences.org/microtas2016/

Keywords

Control and Systems Engineering
Biosensor
Gold nanoparticle
Plasmonic
Whole cell detection

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title = "A novel gold nanoparticle-DNA aptamer-based plasmonic chip for rapid and sensitive detection of bacterial pathogens",

abstract = "Gold nanoparticles (AuNPs)-based biosensors are emerging technologies for rapid detection of pathogens. However, it is very challenging to develop chip-based AuNP-biosensors for whole cells. This paper describes a novel AuNPs-DNA aptamer-based plasmonic assay which allows DNA aptamers to be detached from AuNPs when interacting with bacteria. The new strategy greatly increases the sensitivity and specificity of chip-based whole-cell biosensing.",

keywords = "Control and Systems Engineering, Biosensor, Gold nanoparticle, Plasmonic, Whole cell detection",

author = "Yi Sun and \{Phuoc Long\}, Truong and Anders Wolff and Bang, \{Dang Duong\}",

year = "2016",

language = "English",

pages = "1222--1223",

booktitle = "20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016",

publisher = "Chemical and Biological Microsystems Society",

note = "20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 ; Conference date: 09-10-2016 Through 13-10-2016",

url = "https://microtasconferences.org/microtas2016/",

}

Sun, Y, Phuoc Long, T, Wolff, A & Bang, DD 2016, A novel gold nanoparticle-DNA aptamer-based plasmonic chip for rapid and sensitive detection of bacterial pathogens. in 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. Chemical and Biological Microsystems Society, pp. 1222-1223, 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Dublin, Ireland, 09/10/2016.

A novel gold nanoparticle-DNA aptamer-based plasmonic chip for rapid and sensitive detection of bacterial pathogens. / Sun, Yi; Phuoc Long, Truong; Wolff, Anders et al.
20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016. Chemical and Biological Microsystems Society, 2016. p. 1222-1223.

Research output: Chapter in Book/Report/Conference proceeding › Conference abstract in proceedings › Research › peer-review

TY - ABST

T1 - A novel gold nanoparticle-DNA aptamer-based plasmonic chip for rapid and sensitive detection of bacterial pathogens

AU - Sun, Yi

AU - Phuoc Long, Truong

AU - Wolff, Anders

AU - Bang, Dang Duong

N1 - Conference code: 20

PY - 2016

Y1 - 2016

N2 - Gold nanoparticles (AuNPs)-based biosensors are emerging technologies for rapid detection of pathogens. However, it is very challenging to develop chip-based AuNP-biosensors for whole cells. This paper describes a novel AuNPs-DNA aptamer-based plasmonic assay which allows DNA aptamers to be detached from AuNPs when interacting with bacteria. The new strategy greatly increases the sensitivity and specificity of chip-based whole-cell biosensing.

AB - Gold nanoparticles (AuNPs)-based biosensors are emerging technologies for rapid detection of pathogens. However, it is very challenging to develop chip-based AuNP-biosensors for whole cells. This paper describes a novel AuNPs-DNA aptamer-based plasmonic assay which allows DNA aptamers to be detached from AuNPs when interacting with bacteria. The new strategy greatly increases the sensitivity and specificity of chip-based whole-cell biosensing.

KW - Control and Systems Engineering

KW - Biosensor

KW - Gold nanoparticle

KW - Plasmonic

KW - Whole cell detection

M3 - Conference abstract in proceedings

SP - 1222

EP - 1223

BT - 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016

PB - Chemical and Biological Microsystems Society

T2 - 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Y2 - 9 October 2016 through 13 October 2016

ER -

A novel gold nanoparticle-DNA aptamer-based plasmonic chip for rapid and sensitive detection of bacterial pathogens

Abstract

Conference

Keywords

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