A novel gold nanoparticle-DNA aptamer-based plasmonic chip for rapid and sensitive detection of bacterial pathogens

Yi Sun, Truong Phuoc Long, Anders Wolff, Dang Duong Bang

Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearchpeer-review

Abstract

Gold nanoparticles (AuNPs)-based biosensors are emerging technologies for rapid detection of pathogens. However, it is very challenging to develop chip-based AuNP-biosensors for whole cells. This paper describes a novel AuNPs-DNA aptamer-based plasmonic assay which allows DNA aptamers to be detached from AuNPs when interacting with bacteria. The new strategy greatly increases the sensitivity and specificity of chip-based whole-cell biosensing.
Original languageEnglish
Title of host publication20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016
Number of pages2
PublisherChemical and Biological Microsystems Society
Publication date2016
Pages1222-1223
Publication statusPublished - 2016
Event20th International Conference on Miniaturized Systems for Chemistry and Life Sciences: MicroTAS 2016 - Dublin, Ireland
Duration: 9 Oct 201613 Oct 2016
Conference number: 20
http://www.microtas2016.org/

Conference

Conference20th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Number20
CountryIreland
CityDublin
Period09/10/201613/10/2016
Internet address

Keywords

  • Control and Systems Engineering
  • Biosensor
  • Gold nanoparticle
  • Plasmonic
  • Whole cell detection

Cite this

Sun, Y., Phuoc Long, T., Wolff, A., & Bang, D. D. (2016). A novel gold nanoparticle-DNA aptamer-based plasmonic chip for rapid and sensitive detection of bacterial pathogens. In 20th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2016 (pp. 1222-1223). Chemical and Biological Microsystems Society.