A novel, sensitive and specific method for detecting Rickettsia spp. in archival samples is described. The method involves the use of fluorescently marked oligonucleotide probes for in situ hybridization. Specific hybridization of Ricekttsia was found without problems of cross-reactions with bacterial species shown to cross-react serologically.
|Journal||Journal of Microbiological Methods|
|Publication status||Published - 2009|
- In situ hybridization
- Archival samples