A Novel Familial Cardiac Arrhythmia Syndrome with Widespread ST-Segment Depression

Henning Bundgaard, Christian Jøns, Elisabeth Lodder, Jose Maria Gonzalez-Izarzugaza, Jose A. Romero Herrera, Steen Pehrson, Jacob Tfelt-Hansen, Gustav Ahlberg, Morten S Olesen, Anders G Holst, Hein Wellens, Carin de Villiers, Robert Hastings, Stuart Graham, Arthur A. M. Wilde, Hugh Watkins, Alex Christensen, Søren Brunak

    Research output: Contribution to journalComment/debateResearchpeer-review


    To the Editor: Several classic cardiac genetic disorders have been identified from specific electrocardiographic (ECG) patterns.1-3 Here, we describe five unrelated families, from three different countries, with features that appear to represent
    a previously unrecognized autosomal dominant syndrome. These families were identified at three tertiary referral centers for patients with known or suspected inherited cardiac disorders (as described in the Supplementary Appendix, available
    with the full text of this letter at NEJM.org)
    Original languageEnglish
    JournalThe New England Journal of Medicine
    Pages (from-to)1780-1782
    Publication statusPublished - 2018


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