A Multi-scale, Multi-disciplinary Approach for Assessing the Technological, Economic, and Environmental Performance of Bio-based Chemicals

Markus Herrgard, Sumesh Sukumara, Miguel Angel Campodonico Alt, Kai Zhuang

Research output: Contribution to journalJournal articleResearchpeer-review

Abstract

In recent years, bio-based chemicals have gained interest as a renewable alternative to petrochemicals. However, there is a significant need to assess the technological, biological, economic and environmental feasibility of bio-based chemicals, particularly during the early research phase. Recently, the Multi-scale framework for Sustainable Industrial Chemicals (MuSIC) was introduced to address this issue by integrating modelling approaches at different scales ranging from cellular to ecological scales. This framework can be further extended by incorporating modelling of the petrochemical value chain and the de novo prediction of metabolic pathways connecting existing host metabolism to desirable chemical products. This multiscale, multi-disciplinary framework for quantitative assessment of bio-based chemicals will play a vital role in supporting engineering, strategy and policy decisions as we progress towards a sustainable chemical industry.
Original languageEnglish
JournalBiochemical Society. Transactions
Volume43
Issue number6
Pages (from-to)1151-1156
Number of pages6
ISSN0300-5127
DOIs
Publication statusPublished - 2015

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