A Model-Based Methodology for Simultaneous Design and Control of a Bioethanol Production Process

Merlin Alvarado-Morales, Mohd-Kamaruddin Abd.Hamid, Gürkan Sin, Krist Gernaey, John Woodley, Rafiqul Gani

Research output: Contribution to journalJournal articleResearchpeer-review


In this work, a framework for the simultaneous solution of design and control problems is presented. Within this framework, two methodologies are presented, the integrated process design and controller design (IPDC) methodology and the process-group contribution (PGC) methodology. The concepts of attainable region (AR), driving force (DF), process-group (PG) and reverse simulation are used within these methodologies. The IPDC methodology is used to find the optimal design-control strategy of a process by locating the maximum point in the AR and DF diagrams for reactor and separator, respectively. The PGC methodology is used to generate more efficient separation designs in terms of energy consumption by targeting the separation task at the largest DF. Both methodologies are highlighted through the application of two case studies, a bioethanol production process and a succinic acid production process. In the final discussion, the results are put in context.
Original languageEnglish
JournalComputers & Chemical Engineering
Issue number12
Pages (from-to)2043-2061
Publication statusPublished - 2010

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