A microfluidic control system with re-usable micropump/valve actuator and injection moulded disposable polymer lab-on-a-slide

Minqiang Bu; Ivan R. Perch-Nielsen; Sun Yi; Anders Wolff

doi:10.1109/TRANSDUCERS.2011.5969452

A microfluidic control system with re-usable micropump/valve actuator and injection moulded disposable polymer lab-on-a-slide

Minqiang Bu, Ivan R. Perch-Nielsen, Sun Yi, Anders Wolff

Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

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Abstract

A microfluidic control system consisting of micropump/valves with a re-usable pneumatic actuator and a disposable polymer lab-on-a-slide is presented. The lab-on-a-slide was fabricated using low cost methods, such as injection moulding of TOPAS® cyclic olefin copolymer (COC) slide, lamination of different layers of polymer, and ultrasonic welding of TOPAS® lid to the slide. The re-usable pneumatic actuator not only simplifies the design of the lab-on-a-slide and reduces the fabrication cost, but also reduces the possibility of cross contamination during replacement of the disposable lab-on-a-slide. The experiment results show the micropump is capable of providing a wide range of flow rate (20–300 µL/min), and microvalves provides a reliable fluidic control in the different parts of the system.

Original language	English
Title of host publication	16th International Solid-State Sensors, Actuators and Microsystems Conference
Publisher	IEEE
Publication date	2011
ISBN (Print)	978-1-4577-0157-3
DOIs	https://doi.org/10.1109/TRANSDUCERS.2011.5969452
Publication status	Published - 2011
Event	16th International Solid-State Sensors, Actuators and Microsystems Conference - Beijing, China Duration: 5 Jun 2011 → 9 Jun 2011 Conference number: 16 http://www.transducers11-beijing.org/

Conference

Conference	16th International Solid-State Sensors, Actuators and Microsystems Conference
Number	16
Country/Territory	China
City	Beijing
Period	05/06/2011 → 09/06/2011
Internet address	http://www.transducers11-beijing.org/

Keywords

Microfluidics
Actuators
Micropumps
Purification
Polymers
Valves
Reservoirs

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10.1109/TRANSDUCERS.2011.5969452

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title = "A microfluidic control system with re-usable micropump/valve actuator and injection moulded disposable polymer lab-on-a-slide",

abstract = "A microfluidic control system consisting of micropump/valves with a re-usable pneumatic actuator and a disposable polymer lab-on-a-slide is presented. The lab-on-a-slide was fabricated using low cost methods, such as injection moulding of TOPAS{\textregistered} cyclic olefin copolymer (COC) slide, lamination of different layers of polymer, and ultrasonic welding of TOPAS{\textregistered} lid to the slide. The re-usable pneumatic actuator not only simplifies the design of the lab-on-a-slide and reduces the fabrication cost, but also reduces the possibility of cross contamination during replacement of the disposable lab-on-a-slide. The experiment results show the micropump is capable of providing a wide range of flow rate (20–300 µL/min), and microvalves provides a reliable fluidic control in the different parts of the system.",

keywords = "Microfluidics, Actuators, Micropumps, Purification, Polymers, Valves, Reservoirs",

author = "Minqiang Bu and Perch-Nielsen, {Ivan R.} and Sun Yi and Anders Wolff",

year = "2011",

doi = "10.1109/TRANSDUCERS.2011.5969452",

language = "English",

isbn = "978-1-4577-0157-3",

booktitle = "16th International Solid-State Sensors, Actuators and Microsystems Conference",

publisher = "IEEE",

address = "United States",

note = "16th International Solid-State Sensors, Actuators and Microsystems Conference, TRANSDUCERS'11 ; Conference date: 05-06-2011 Through 09-06-2011",

url = "http://www.transducers11-beijing.org/",

}

Bu, M, Perch-Nielsen, IR, Yi, S & Wolff, A 2011, A microfluidic control system with re-usable micropump/valve actuator and injection moulded disposable polymer lab-on-a-slide. in 16th International Solid-State Sensors, Actuators and Microsystems Conference. IEEE, 16th International Solid-State Sensors, Actuators and Microsystems Conference, Beijing, China, 05/06/2011. https://doi.org/10.1109/TRANSDUCERS.2011.5969452

A microfluidic control system with re-usable micropump/valve actuator and injection moulded disposable polymer lab-on-a-slide. / Bu, Minqiang; Perch-Nielsen, Ivan R.; Yi, Sun ; Wolff, Anders.

16th International Solid-State Sensors, Actuators and Microsystems Conference. IEEE, 2011.

Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

TY - GEN

T1 - A microfluidic control system with re-usable micropump/valve actuator and injection moulded disposable polymer lab-on-a-slide

AU - Bu, Minqiang

AU - Perch-Nielsen, Ivan R.

AU - Yi, Sun

AU - Wolff, Anders

N1 - Conference code: 16

PY - 2011

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N2 - A microfluidic control system consisting of micropump/valves with a re-usable pneumatic actuator and a disposable polymer lab-on-a-slide is presented. The lab-on-a-slide was fabricated using low cost methods, such as injection moulding of TOPAS® cyclic olefin copolymer (COC) slide, lamination of different layers of polymer, and ultrasonic welding of TOPAS® lid to the slide. The re-usable pneumatic actuator not only simplifies the design of the lab-on-a-slide and reduces the fabrication cost, but also reduces the possibility of cross contamination during replacement of the disposable lab-on-a-slide. The experiment results show the micropump is capable of providing a wide range of flow rate (20–300 µL/min), and microvalves provides a reliable fluidic control in the different parts of the system.

AB - A microfluidic control system consisting of micropump/valves with a re-usable pneumatic actuator and a disposable polymer lab-on-a-slide is presented. The lab-on-a-slide was fabricated using low cost methods, such as injection moulding of TOPAS® cyclic olefin copolymer (COC) slide, lamination of different layers of polymer, and ultrasonic welding of TOPAS® lid to the slide. The re-usable pneumatic actuator not only simplifies the design of the lab-on-a-slide and reduces the fabrication cost, but also reduces the possibility of cross contamination during replacement of the disposable lab-on-a-slide. The experiment results show the micropump is capable of providing a wide range of flow rate (20–300 µL/min), and microvalves provides a reliable fluidic control in the different parts of the system.

KW - Microfluidics

KW - Actuators

KW - Micropumps

KW - Purification

KW - Polymers

KW - Valves

KW - Reservoirs

U2 - 10.1109/TRANSDUCERS.2011.5969452

DO - 10.1109/TRANSDUCERS.2011.5969452

M3 - Article in proceedings

SN - 978-1-4577-0157-3

BT - 16th International Solid-State Sensors, Actuators and Microsystems Conference

PB - IEEE

T2 - 16th International Solid-State Sensors, Actuators and Microsystems Conference

Y2 - 5 June 2011 through 9 June 2011

ER -

A microfluidic control system with re-usable micropump/valve actuator and injection moulded disposable polymer lab-on-a-slide

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Keywords

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