A microfluidic cell culture device with integrated microelectrodes for barrier studies.

Hsih-Yin Tan, Martin Dufva, Jörg P. Kutter, Thomas Lars Andresen

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    Abstract

    We present an eight cell culture microfluidic device fabricated using thiol-ene ‘click’ chemistry with embedded microelectrodes for evaluating barrier properties of human intestinal epithelial cells. The capability of the microelectrodes for trans-epithelial electrical resistance (TEER) measurements was demonstrated by using confluent human colorectal epithelial cells (Caco-2) and rat fibroblast (CT 26) cells cultured in the microfluidic device.
    Original languageEnglish
    Publication date2016
    Publication statusPublished - 2016
    EventOrgan-on-a-Chip World Congress & 3D-Culture 2016 - Boston, MA, United States
    Duration: 7 Jul 20168 Jul 2016

    Conference

    ConferenceOrgan-on-a-Chip World Congress & 3D-Culture 2016
    CountryUnited States
    CityBoston, MA
    Period07/07/201608/07/2016

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