A Methodology for Development of a Pedagogical Simulation Tool used in Fermentation Applications

Research output: Chapter in Book/Report/Conference proceedingBook chapter – Annual report year: 2019Researchpeer-review

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In this work, a holistic methodology was developed and implemented in a computeraided framework with the purpose of establishing a pedagogical simulation tool for bioprocess applications. The methodology integrates the development of a process simulator with the use of gamification elements to improve the pedagogical experience. Moreover, model development and reuse was incorporated into the framework through creating a generic model template. The application of the methodology was demonstrated by the simulation of a batch fermentation process of Saccharomyces cerevisiae cultivated under aerobic conditions with glucose as substrate, thereby, demonstrating mixed metabolism dynamics and considering the inhibition of ethanol consumption due to the presence of glucose with an integrated learning design and gamification elements. The learning experience, done with beta users with different previous levels of knowledge about fermentation processes, confirmed an interest for using gamification for training chemical engineering, biochemical engineering, and biotechnology students.

Original languageEnglish
Title of host publication Proceedings of the 13th International Symposium on Process Systems Engineering – PSE 2018
EditorsMario R. Eden, Marianthi G. Ierapetritou, Gavin P. Towler
Number of pages6
Publication date2018
ISBN (Electronic)978-0-444-64241-7
Publication statusPublished - 2018
Event13th International Symposium on Process Systems Engineering (PSE 2018) - San DIego, United States
Duration: 1 Jul 20185 Jul 2018


Conference13th International Symposium on Process Systems Engineering (PSE 2018)
CountryUnited States
CitySan DIego
SeriesComputer Aided Chemical Engineering
CitationsWeb of Science® Times Cited: No match on DOI

    Research areas

  • Fermentation, Gamification, Learning experience, Methodology, Simulator

ID: 184363132