Abstract
Metabolomics is a promising tool for searching out new biomarkers and the development of hypotheses in nutrition research. This chapter will describe the design of human dietary intervention studies where samples are collected for metabolomics analyses as well as the analytical issues and data interpretation. Design considerations for metabolomic studies include the overall structure of the study as well as the control group, sample collection and handling, sample storage, sample analysis, quality control measures and plans for data analyses. Suggestions for designing feasible and ethical dietary studies are given.
Original language | English |
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Title of host publication | Design of human nutrigenomics studies |
Editors | S. Astley, L. Penn |
Number of pages | 9 |
Publisher | Wageningen Academic Publishers |
Publication date | 2009 |
Pages | 21-29 |
Chapter | 3 |
ISBN (Electronic) | 978-90-8686-094-4 |
DOIs | |
Publication status | Published - 2009 |
Keywords
- Social Sciences (all)
- Agricultural and Biological Sciences (all)
- Engineering (all)