A Metabolic Switch

Poul G. Hjorth

A Metabolic Switch

Poul G. Hjorth (Invited author)

Research output: Contribution to conference › Paper › Research › peer-review

Abstract

Our muscles are metabolically flexible, i.e., they are capable of `switching' between two types of oxidation: (1) when fasting, a predominantly lipid oxidation with high rates of fatty acid uptake, and (2) when fed, suppression of lipid oxidation in favour of increased glucose uptake, oxidation and storage, in response to insulin. One of the many manifestations of obesity and Type 2 diabetes is an insulin resistance of the skeletal muscles, which suppresses this metabolic switch. This talk describes recent development of a low-dimensional system of ODEs that model the metabolic switch, displaying a sensitivity to insulin concentration which matches well with clinical data.

Original language	English
Publication date	2008
Publication status	Published - 2008
Event	Joint Mathematicsl Weekend - University of Copenhagen Duration: 1 Jan 2008 → …

Conference

Conference	Joint Mathematicsl Weekend
City	University of Copenhagen
Period	01/01/2008 → …

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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http://www.math.ku.dk/english/research/conferences/emsweekend/

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M3 - Paper

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A Metabolic Switch

Abstract

Conference

UN SDGs

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