A mechanoelectrical mechanism for detection of sound envelopes in the hearing organ

Alfred L Nuttall; Anthony J Ricci; George Burwood; James M Harte; Stefan Stenfelt; Per Cayé-Thomasen; Tianying Ren; Sripriya Ramamoorthy; Yuan Zhang; Teresa Wilson; Thomas Lunner; Brian C J Moore; Anders Fridberger

doi:10.1038/s41467-018-06725-w

A mechanoelectrical mechanism for detection of sound envelopes in the hearing organ

Alfred L Nuttall^*, Anthony J Ricci, George Burwood, James M Harte, Stefan Stenfelt, Per Cayé-Thomasen, Tianying Ren, Sripriya Ramamoorthy, Yuan Zhang, Teresa Wilson, Thomas Lunner, Brian C J Moore, Anders Fridberger

^*Corresponding author for this work

Research output: Contribution to journal › Journal article › Research › peer-review

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Abstract

To understand speech, the slowly varying outline, or envelope, of the acoustic stimulus is used to distinguish words. A small amount of information about the envelope is sufficient for speech recognition, but the mechanism used by the auditory system to extract the envelope is not known. Several different theories have been proposed, including envelope detection by auditory nerve dendrites as well as various mechanisms involving the sensory hair cells. We used recordings from human and animal inner ears to show that the dominant mechanism for envelope detection is distortion introduced by mechanoelectrical transduction channels. This electrical distortion, which is not apparent in the sound-evoked vibrations of the basilar membrane, tracks the envelope, excites the auditory nerve, and transmits information about the shape of the envelope to the brain.

Original language	English
Article number	4175
Journal	Nature Communications
Volume	9
Issue number	1
Number of pages	11
ISSN	2041-1723
DOIs	https://doi.org/10.1038/s41467-018-06725-w
Publication status	Published - 2018

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This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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abstract = "To understand speech, the slowly varying outline, or envelope, of the acoustic stimulus is used to distinguish words. A small amount of information about the envelope is sufficient for speech recognition, but the mechanism used by the auditory system to extract the envelope is not known. Several different theories have been proposed, including envelope detection by auditory nerve dendrites as well as various mechanisms involving the sensory hair cells. We used recordings from human and animal inner ears to show that the dominant mechanism for envelope detection is distortion introduced by mechanoelectrical transduction channels. This electrical distortion, which is not apparent in the sound-evoked vibrations of the basilar membrane, tracks the envelope, excites the auditory nerve, and transmits information about the shape of the envelope to the brain.",

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PY - 2018

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N2 - To understand speech, the slowly varying outline, or envelope, of the acoustic stimulus is used to distinguish words. A small amount of information about the envelope is sufficient for speech recognition, but the mechanism used by the auditory system to extract the envelope is not known. Several different theories have been proposed, including envelope detection by auditory nerve dendrites as well as various mechanisms involving the sensory hair cells. We used recordings from human and animal inner ears to show that the dominant mechanism for envelope detection is distortion introduced by mechanoelectrical transduction channels. This electrical distortion, which is not apparent in the sound-evoked vibrations of the basilar membrane, tracks the envelope, excites the auditory nerve, and transmits information about the shape of the envelope to the brain.

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A mechanoelectrical mechanism for detection of sound envelopes in the hearing organ

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