A General and Convenient Method for the Rhodium-Catalyzed Decarbonylation of Aldehydes

Michael Kreis, Anders Palmelund, Lennart Bunch, Robert Madsen

Research output: Contribution to journalJournal articlepeer-review

Abstract

A practical protocol for the decarbonylation of a wide range of aldehydes has been developed by using commercially available RhCl3x3H2O and dppp in a diglyme solution. This method gives rise to decarbonylated products in good to high yield and is particularly useful because of its experimental simplicity, high generality and excellent level of functional group tolerance. The reaction has been applied in a tandem Oppenauer oxidation-decarbonylation sequence, which removes a hydroxymethyl group in one operation
Original languageEnglish
JournalAdvanced Synthesis & Catalysis
Volume348
Issue number15
Pages (from-to)2148-2154
ISSN1615-4150
DOIs
Publication statusPublished - 2006

Keywords

  • Aldehydes
  • Decarbonylation
  • Oppenauer oxidation
  • Rhodium
  • Tandem reaction

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