A General and Convenient Method for the Rhodium-Catalyzed Decarbonylation of Aldehydes

Michael Kreis; Anders Palmelund; Lennart Bunch; Robert Madsen

doi:10.1002/adsc.200600228

A General and Convenient Method for the Rhodium-Catalyzed Decarbonylation of Aldehydes

Michael Kreis, Anders Palmelund, Lennart Bunch, Robert Madsen

Department of Chemistry

Research output: Contribution to journal › Journal article › peer-review

Abstract

A practical protocol for the decarbonylation of a wide range of aldehydes has been developed by using commercially available RhCl3x3H2O and dppp in a diglyme solution. This method gives rise to decarbonylated products in good to high yield and is particularly useful because of its experimental simplicity, high generality and excellent level of functional group tolerance. The reaction has been applied in a tandem Oppenauer oxidation-decarbonylation sequence, which removes a hydroxymethyl group in one operation

Original language	English
Journal	Advanced Synthesis & Catalysis
Volume	348
Issue number	15
Pages (from-to)	2148-2154
ISSN	1615-4150
DOIs	https://doi.org/10.1002/adsc.200600228
Publication status	Published - 2006

Keywords

Aldehydes
Decarbonylation
Oppenauer oxidation
Rhodium
Tandem reaction

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10.1002/adsc.200600228

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title = "A General and Convenient Method for the Rhodium-Catalyzed Decarbonylation of Aldehydes",

abstract = "A practical protocol for the decarbonylation of a wide range of aldehydes has been developed by using commercially available RhCl3x3H2O and dppp in a diglyme solution. This method gives rise to decarbonylated products in good to high yield and is particularly useful because of its experimental simplicity, high generality and excellent level of functional group tolerance. The reaction has been applied in a tandem Oppenauer oxidation-decarbonylation sequence, which removes a hydroxymethyl group in one operation",

keywords = "Aldehydes, Decarbonylation, Oppenauer oxidation, Rhodium, Tandem reaction",

author = "Michael Kreis and Anders Palmelund and Lennart Bunch and Robert Madsen",

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language = "English",

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T1 - A General and Convenient Method for the Rhodium-Catalyzed Decarbonylation of Aldehydes

AU - Kreis, Michael

AU - Palmelund, Anders

AU - Bunch, Lennart

AU - Madsen, Robert

PY - 2006

Y1 - 2006

N2 - A practical protocol for the decarbonylation of a wide range of aldehydes has been developed by using commercially available RhCl3x3H2O and dppp in a diglyme solution. This method gives rise to decarbonylated products in good to high yield and is particularly useful because of its experimental simplicity, high generality and excellent level of functional group tolerance. The reaction has been applied in a tandem Oppenauer oxidation-decarbonylation sequence, which removes a hydroxymethyl group in one operation

AB - A practical protocol for the decarbonylation of a wide range of aldehydes has been developed by using commercially available RhCl3x3H2O and dppp in a diglyme solution. This method gives rise to decarbonylated products in good to high yield and is particularly useful because of its experimental simplicity, high generality and excellent level of functional group tolerance. The reaction has been applied in a tandem Oppenauer oxidation-decarbonylation sequence, which removes a hydroxymethyl group in one operation

KW - Aldehydes

KW - Decarbonylation

KW - Oppenauer oxidation

KW - Rhodium

KW - Tandem reaction

U2 - 10.1002/adsc.200600228

DO - 10.1002/adsc.200600228

M3 - Journal article

VL - 348

SP - 2148

EP - 2154

JO - Advanced Synthesis & Catalysis

JF - Advanced Synthesis & Catalysis

SN - 1615-4150

IS - 15

ER -

A General and Convenient Method for the Rhodium-Catalyzed Decarbonylation of Aldehydes

Abstract

Keywords

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