A family of microbial lysine transporter polypeptides

Sailesh Malla (Inventor), Morten Otto Alexander Sommer (Inventor), Eric van der Helm (Inventor), Stefan Wieschalka (Inventor), Jochen Förster (Inventor)

Research output: Patent

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Abstract

The present invention provides a genetically modified microbial cell for production of lysine, comprising a transgene encoding a polypeptide capable of exporting lysine from the cell. The genetically modified microbial cell for production of lysine may be further characterized by genetic modifications that confer reduced lysine metabolism and/or enhanced lysine synthesis as compared to the parent cell from which said genetically modified cell was derived. The invention further provides a method for producing lysine using the genetically modified microbial cell. The invention further provides a novel family of lysine transporter polypeptides; and the use of said polypeptide to enhance production of extracellular lysine in a microbial cell.

Original languageEnglish
IPCC12P 13/ 08 A I
Patent numberWO2017085241
Filing date26/05/2017
CountryInternational Bureau of the World Intellectual Property Organization (WIPO)
Priority date19/11/2015
Priority numberEP20150195401
Publication statusPublished - 26 May 2017

Cite this

Malla, S., Sommer, M. O. A., van der Helm, E., Wieschalka, S., & Förster, J. (2017). IPC No. C12P 13/ 08 A I. A family of microbial lysine transporter polypeptides. (Patent No. WO2017085241).