A Comparison of FFD-based Nonrigid Registration and AAMs Applied to Myocardial Perfusion MRI

Hildur Ólafsdóttir, Mikkel Bille Stegmann, Bjarne Kjær Ersbøll, Henrik B.W. Larsson

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

    Abstract

    Little work has been done on comparing the performance of statistical model-based approaches and nonrigid registration algorithms. This paper deals with the qualitative and quantitative comparison of active appearance models (AAMs) and a nonrigid registration algorithm based on free-form deformations (FFDs). AAMs are known to be much faster than nonrigid registration algorithms. On the other hand nonrigid registration algorithms are independent of a training set as required to build an AAM. To obtain a further comparison of the two methods, they are both applied to automatically register multi-slice myocardial perfusion images. The images are acquired by magnetic resonance imaging, from infarct patients. A registration of these sequences is crucial for clinical practice, which currently is subjected to manual labor. In the paper, the pros and cons of the two registration approaches are discussed and qualitative and quantitative comparisons are provided. The quantitative comparison is obtained by an analysis of variance of landmark errors, i.e. point to point and point to curve errors. Even though the FFD-based approach does not include a training phase it gave similar accuracy as the AAMs in terms of point to point errors. For the point to curve errors the AAMs provided higher accuracy. In both cases AAMs gave higher precision due to the training procedure.
    Original languageEnglish
    Title of host publicationInternational Symposium on Medical Imaging 2006, San Diego, CA
    PublisherThe International Society for Optical Engineering (SPIE)
    Publication date2006
    Publication statusPublished - 2006

    Cite this

    Ólafsdóttir, H., Stegmann, M. B., Ersbøll, B. K., & Larsson, H. B. W. (2006). A Comparison of FFD-based Nonrigid Registration and AAMs Applied to Myocardial Perfusion MRI. In International Symposium on Medical Imaging 2006, San Diego, CA The International Society for Optical Engineering (SPIE).
    Ólafsdóttir, Hildur ; Stegmann, Mikkel Bille ; Ersbøll, Bjarne Kjær ; Larsson, Henrik B.W. / A Comparison of FFD-based Nonrigid Registration and AAMs Applied to Myocardial Perfusion MRI. International Symposium on Medical Imaging 2006, San Diego, CA. The International Society for Optical Engineering (SPIE), 2006.
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    title = "A Comparison of FFD-based Nonrigid Registration and AAMs Applied to Myocardial Perfusion MRI",
    abstract = "Little work has been done on comparing the performance of statistical model-based approaches and nonrigid registration algorithms. This paper deals with the qualitative and quantitative comparison of active appearance models (AAMs) and a nonrigid registration algorithm based on free-form deformations (FFDs). AAMs are known to be much faster than nonrigid registration algorithms. On the other hand nonrigid registration algorithms are independent of a training set as required to build an AAM. To obtain a further comparison of the two methods, they are both applied to automatically register multi-slice myocardial perfusion images. The images are acquired by magnetic resonance imaging, from infarct patients. A registration of these sequences is crucial for clinical practice, which currently is subjected to manual labor. In the paper, the pros and cons of the two registration approaches are discussed and qualitative and quantitative comparisons are provided. The quantitative comparison is obtained by an analysis of variance of landmark errors, i.e. point to point and point to curve errors. Even though the FFD-based approach does not include a training phase it gave similar accuracy as the AAMs in terms of point to point errors. For the point to curve errors the AAMs provided higher accuracy. In both cases AAMs gave higher precision due to the training procedure.",
    keywords = "Magnetic Resonance Imaging, Active Appearance Models, Nonrigid registration, Myocardial perfusion",
    author = "Hildur {\'O}lafsd{\'o}ttir and Stegmann, {Mikkel Bille} and Ersb{\o}ll, {Bjarne Kj{\ae}r} and Larsson, {Henrik B.W.}",
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    Ólafsdóttir, H, Stegmann, MB, Ersbøll, BK & Larsson, HBW 2006, A Comparison of FFD-based Nonrigid Registration and AAMs Applied to Myocardial Perfusion MRI. in International Symposium on Medical Imaging 2006, San Diego, CA. The International Society for Optical Engineering (SPIE).

    A Comparison of FFD-based Nonrigid Registration and AAMs Applied to Myocardial Perfusion MRI. / Ólafsdóttir, Hildur; Stegmann, Mikkel Bille; Ersbøll, Bjarne Kjær; Larsson, Henrik B.W.

    International Symposium on Medical Imaging 2006, San Diego, CA. The International Society for Optical Engineering (SPIE), 2006.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

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    AU - Ersbøll, Bjarne Kjær

    AU - Larsson, Henrik B.W.

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    N2 - Little work has been done on comparing the performance of statistical model-based approaches and nonrigid registration algorithms. This paper deals with the qualitative and quantitative comparison of active appearance models (AAMs) and a nonrigid registration algorithm based on free-form deformations (FFDs). AAMs are known to be much faster than nonrigid registration algorithms. On the other hand nonrigid registration algorithms are independent of a training set as required to build an AAM. To obtain a further comparison of the two methods, they are both applied to automatically register multi-slice myocardial perfusion images. The images are acquired by magnetic resonance imaging, from infarct patients. A registration of these sequences is crucial for clinical practice, which currently is subjected to manual labor. In the paper, the pros and cons of the two registration approaches are discussed and qualitative and quantitative comparisons are provided. The quantitative comparison is obtained by an analysis of variance of landmark errors, i.e. point to point and point to curve errors. Even though the FFD-based approach does not include a training phase it gave similar accuracy as the AAMs in terms of point to point errors. For the point to curve errors the AAMs provided higher accuracy. In both cases AAMs gave higher precision due to the training procedure.

    AB - Little work has been done on comparing the performance of statistical model-based approaches and nonrigid registration algorithms. This paper deals with the qualitative and quantitative comparison of active appearance models (AAMs) and a nonrigid registration algorithm based on free-form deformations (FFDs). AAMs are known to be much faster than nonrigid registration algorithms. On the other hand nonrigid registration algorithms are independent of a training set as required to build an AAM. To obtain a further comparison of the two methods, they are both applied to automatically register multi-slice myocardial perfusion images. The images are acquired by magnetic resonance imaging, from infarct patients. A registration of these sequences is crucial for clinical practice, which currently is subjected to manual labor. In the paper, the pros and cons of the two registration approaches are discussed and qualitative and quantitative comparisons are provided. The quantitative comparison is obtained by an analysis of variance of landmark errors, i.e. point to point and point to curve errors. Even though the FFD-based approach does not include a training phase it gave similar accuracy as the AAMs in terms of point to point errors. For the point to curve errors the AAMs provided higher accuracy. In both cases AAMs gave higher precision due to the training procedure.

    KW - Magnetic Resonance Imaging

    KW - Active Appearance Models

    KW - Nonrigid registration

    KW - Myocardial perfusion

    M3 - Article in proceedings

    BT - International Symposium on Medical Imaging 2006, San Diego, CA

    PB - The International Society for Optical Engineering (SPIE)

    ER -

    Ólafsdóttir H, Stegmann MB, Ersbøll BK, Larsson HBW. A Comparison of FFD-based Nonrigid Registration and AAMs Applied to Myocardial Perfusion MRI. In International Symposium on Medical Imaging 2006, San Diego, CA. The International Society for Optical Engineering (SPIE). 2006