A comparative study of noise in supercontinuum light sources for ultra-high resolution optical coherence tomography

Sanjuan-Ferrer, Maria J.; Ivan Bravo Gonzalo; Magalie Bondu; Rasmus Dybbro Engelsholm; Thomas Feuchter; Peter M. Moselund; Lasse Leick; Ole Bang; Adrian Podoleanu

doi:10.1117/12.2251500

A comparative study of noise in supercontinuum light sources for ultra-high resolution optical coherence tomography

Sanjuan-Ferrer, Maria J. , Ivan Bravo Gonzalo, Magalie Bondu, Rasmus Dybbro Engelsholm, Thomas Feuchter, Peter M. Moselund, Lasse Leick, Ole Bang, Adrian Podoleanu

Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

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Abstract

Supercontinuum (SC) light is a well-established technology, which finds applications in several domains ranging from chemistry to material science and imaging systems [1-2]. More specifically, its ultra-wide optical bandwidth and high average power make it an ideal tool for Optical Coherence Tomography (OCT). Over the last 5 years, numerous examples have demonstrated its high potential [3-4] in this context. However, SC light sources present pulse-to-pulse intensity variation that can limit the performance of any OCT system [5] by degrading their signal to noise ratio (SNR). To this goal, we have studied and compared the noise of several SC light sources and evaluated how their noise properties affect the performance of Ultra-High Resolution OCT (UHR-OCT) at 1300 nm. We have measured several SC light sources with different parameters (pulse length, energy, seed repetition rate, etc.). We illustrate the different noise measurements and their impact on a state of the art UHR-OCT system producing images of skin. The sensitivity of the system was higher than 95 dB, with an axial resolution below 4μm.

Original language	English
Title of host publication	Proceedings of SPIE
Number of pages	6
Volume	10056
Publisher	SPIE - International Society for Optical Engineering
Publication date	2017
Article number	100560O
DOIs	https://doi.org/10.1117/12.2251500
Publication status	Published - 2017
Event	Design and Quality for Biomedical Technologies X - San Francisco, United States Duration: 28 Jan 2017 → 29 Jan 2017 Conference number: 10

Conference

Conference	Design and Quality for Biomedical Technologies X
Number	10
Country/Territory	United States
City	San Francisco
Period	28/01/2017 → 29/01/2017

Series	Proceedings of SPIE - The International Society for Optical Engineering
ISSN	0277-786X

Bibliographical note

Copyright 2017 Society of Photo Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic electronic or print reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.

Keywords

Optical and laser radiation (medical uses)
Patient diagnostic methods and instrumentation
Optical and laser radiation (biomedical imaging/measurement)
Light sources
Biomedical optical imaging
Skin
Supercontinuum generation
Skin images
Noise measurements
Noise properties
Signal-to-noise-ratio
Pulse-to-pulse intensity variation
Ultra-wide optical bandwidth
Ultra-high resolution optical coherence tomography
Supercontinuum light sources

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Maria J. , S.-F., Bravo Gonzalo, I., Bondu, M., Engelsholm, R. D., Feuchter, T., Moselund, P. M., Leick, L., Bang, O., & Podoleanu, A. (2017). A comparative study of noise in supercontinuum light sources for ultra-high resolution optical coherence tomography. In Proceedings of SPIE (Vol. 10056). Article 100560O SPIE - International Society for Optical Engineering. https://doi.org/10.1117/12.2251500

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abstract = "Supercontinuum (SC) light is a well-established technology, which finds applications in several domains ranging from chemistry to material science and imaging systems [1-2]. More specifically, its ultra-wide optical bandwidth and high average power make it an ideal tool for Optical Coherence Tomography (OCT). Over the last 5 years, numerous examples have demonstrated its high potential [3-4] in this context. However, SC light sources present pulse-to-pulse intensity variation that can limit the performance of any OCT system [5] by degrading their signal to noise ratio (SNR). To this goal, we have studied and compared the noise of several SC light sources and evaluated how their noise properties affect the performance of Ultra-High Resolution OCT (UHR-OCT) at 1300 nm. We have measured several SC light sources with different parameters (pulse length, energy, seed repetition rate, etc.). We illustrate the different noise measurements and their impact on a state of the art UHR-OCT system producing images of skin. The sensitivity of the system was higher than 95 dB, with an axial resolution below 4μm.",

keywords = "Optical and laser radiation (medical uses), Patient diagnostic methods and instrumentation, Optical and laser radiation (biomedical imaging/measurement), Light sources, Biomedical optical imaging, Skin, Supercontinuum generation, Skin images, Noise measurements, Noise properties, Signal-to-noise-ratio, Pulse-to-pulse intensity variation, Ultra-wide optical bandwidth, Ultra-high resolution optical coherence tomography, Supercontinuum light sources",

author = "{Maria J.}, Sanjuan-Ferrer, and {Bravo Gonzalo}, Ivan and Magalie Bondu and Engelsholm, {Rasmus Dybbro} and Thomas Feuchter and Moselund, {Peter M.} and Lasse Leick and Ole Bang and Adrian Podoleanu",

note = "Copyright 2017 Society of Photo Optical Instrumentation Engineers. One print or electronic copy may be made for personal use only. Systematic electronic or print reproduction and distribution, duplication of any material in this paper for a fee or for commercial purposes, or modification of the content of the paper are prohibited.; Design and Quality for Biomedical Technologies X ; Conference date: 28-01-2017 Through 29-01-2017",

year = "2017",

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Maria J. , S-F, Bravo Gonzalo, I, Bondu, M, Engelsholm, RD, Feuchter, T, Moselund, PM, Leick, L, Bang, O & Podoleanu, A 2017, A comparative study of noise in supercontinuum light sources for ultra-high resolution optical coherence tomography. in Proceedings of SPIE. vol. 10056, 100560O, SPIE - International Society for Optical Engineering, Proceedings of SPIE - The International Society for Optical Engineering, Design and Quality for Biomedical Technologies X, San Francisco, California, United States, 28/01/2017. https://doi.org/10.1117/12.2251500

A comparative study of noise in supercontinuum light sources for ultra-high resolution optical coherence tomography. / Maria J. , Sanjuan-Ferrer,; Bravo Gonzalo, Ivan; Bondu, Magalie et al.
Proceedings of SPIE. Vol. 10056 SPIE - International Society for Optical Engineering, 2017. 100560O (Proceedings of SPIE - The International Society for Optical Engineering).

Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review

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T1 - A comparative study of noise in supercontinuum light sources for ultra-high resolution optical coherence tomography

AU - Maria J. , Sanjuan-Ferrer,

AU - Bravo Gonzalo, Ivan

AU - Bondu, Magalie

AU - Engelsholm, Rasmus Dybbro

AU - Feuchter, Thomas

AU - Moselund, Peter M.

AU - Leick, Lasse

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AB - Supercontinuum (SC) light is a well-established technology, which finds applications in several domains ranging from chemistry to material science and imaging systems [1-2]. More specifically, its ultra-wide optical bandwidth and high average power make it an ideal tool for Optical Coherence Tomography (OCT). Over the last 5 years, numerous examples have demonstrated its high potential [3-4] in this context. However, SC light sources present pulse-to-pulse intensity variation that can limit the performance of any OCT system [5] by degrading their signal to noise ratio (SNR). To this goal, we have studied and compared the noise of several SC light sources and evaluated how their noise properties affect the performance of Ultra-High Resolution OCT (UHR-OCT) at 1300 nm. We have measured several SC light sources with different parameters (pulse length, energy, seed repetition rate, etc.). We illustrate the different noise measurements and their impact on a state of the art UHR-OCT system producing images of skin. The sensitivity of the system was higher than 95 dB, with an axial resolution below 4μm.

KW - Optical and laser radiation (medical uses)

KW - Patient diagnostic methods and instrumentation

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KW - Skin

KW - Supercontinuum generation

KW - Skin images

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KW - Noise properties

KW - Signal-to-noise-ratio

KW - Pulse-to-pulse intensity variation

KW - Ultra-wide optical bandwidth

KW - Ultra-high resolution optical coherence tomography

KW - Supercontinuum light sources

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DO - 10.1117/12.2251500

M3 - Article in proceedings

VL - 10056

T3 - Proceedings of SPIE - The International Society for Optical Engineering

BT - Proceedings of SPIE

PB - SPIE - International Society for Optical Engineering

T2 - Design and Quality for Biomedical Technologies X

Y2 - 28 January 2017 through 29 January 2017

ER -

Maria J. SF, Bravo Gonzalo I, Bondu M, Engelsholm RD, Feuchter T, Moselund PM et al. A comparative study of noise in supercontinuum light sources for ultra-high resolution optical coherence tomography. In Proceedings of SPIE. Vol. 10056. SPIE - International Society for Optical Engineering. 2017. 100560O. (Proceedings of SPIE - The International Society for Optical Engineering). doi: 10.1117/12.2251500

A comparative study of noise in supercontinuum light sources for ultra-high resolution optical coherence tomography

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Bibliographical note

Keywords

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