A comparative dose-response study of prophylactic peanut allergy SLIT and EPIT in brown Norway rats

E. Lindberg; E. Eller; S. Yadav; A. I. Sancho; N. S. R. Pedersen; N. Chakrapani; K. B. Sylvestersen; S. Gupta; K. L. Bøgh

A comparative dose-response study of prophylactic peanut allergy SLIT and EPIT in brown Norway rats

E. Lindberg
, E. Eller^*
, S. Yadav
, A. I. Sancho
, N. S. R. Pedersen
, N. Chakrapani
, K. B. Sylvestersen
, S. Gupta
, K. L. Bøgh

^*Corresponding author for this work

ALK

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

Abstract

Peanut allergy immunotherapy (PA-IT) is emerging as a viable treatment option for peanut allergic patients. Various routes of PA-IT administration have been investigated in the search for an efficient and safe IT approach. Here, we performed a comprehensive investigation of the humoral immune response during the mucosal administration of peanut protein extract (PPE) via oral (O), intragastric (IG) and sublingual (SL) routes in a Brown Norway rat model of PA-IT.

Original language	English
Article number	001592
Journal	Allergy: European Journal of Allergy and Clinical Immunology
Volume	79
Issue number	S113
Pages (from-to)	276-276
Number of pages	1
ISSN	0105-4538
Publication status	Published - 2024
Event	European Academy of Allergy and Clinical Immunology Hybrid Congress 2024 - Valencia, Spain Duration: 31 May 2024 → 3 Jun 2024

Conference

Conference	European Academy of Allergy and Clinical Immunology Hybrid Congress 2024
Country/Territory	Spain
City	Valencia
Period	31/05/2024 → 03/06/2024

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title = "A comparative dose-response study of prophylactic peanut allergy SLIT and EPIT in brown Norway rats",

abstract = "Peanut allergy immunotherapy (PA-IT) is emerging as a viable treatment option for peanut allergic patients. Various routes of PA-IT administration have been investigated in the search for an efficient and safe IT approach. Here, we performed a comprehensive investigation of the humoral immune response during the mucosal administration of peanut protein extract (PPE) via oral (O), intragastric (IG) and sublingual (SL) routes in a Brown Norway rat model of PA-IT.",

author = "E. Lindberg and E. Eller and S. Yadav and Sancho, \{A. I.\} and Pedersen, \{N. S. R.\} and N. Chakrapani and Sylvestersen, \{K. B.\} and S. Gupta and B{\o}gh, \{K. L.\}",

year = "2024",

language = "English",

volume = "79",

pages = "276--276",

journal = "Allergy: European Journal of Allergy and Clinical Immunology",

issn = "0105-4538",

publisher = "Wiley-Blackwell",

number = "S113",

note = "European Academy of Allergy and Clinical Immunology Hybrid Congress 2024, EAACI Congress 2024 ; Conference date: 31-05-2024 Through 03-06-2024",

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TY - ABST

T1 - A comparative dose-response study of prophylactic peanut allergy SLIT and EPIT in brown Norway rats

AU - Lindberg, E.

AU - Eller, E.

AU - Yadav, S.

AU - Sancho, A. I.

AU - Pedersen, N. S. R.

AU - Chakrapani, N.

AU - Sylvestersen, K. B.

AU - Gupta, S.

AU - Bøgh, K. L.

PY - 2024

Y1 - 2024

N2 - Peanut allergy immunotherapy (PA-IT) is emerging as a viable treatment option for peanut allergic patients. Various routes of PA-IT administration have been investigated in the search for an efficient and safe IT approach. Here, we performed a comprehensive investigation of the humoral immune response during the mucosal administration of peanut protein extract (PPE) via oral (O), intragastric (IG) and sublingual (SL) routes in a Brown Norway rat model of PA-IT.

AB - Peanut allergy immunotherapy (PA-IT) is emerging as a viable treatment option for peanut allergic patients. Various routes of PA-IT administration have been investigated in the search for an efficient and safe IT approach. Here, we performed a comprehensive investigation of the humoral immune response during the mucosal administration of peanut protein extract (PPE) via oral (O), intragastric (IG) and sublingual (SL) routes in a Brown Norway rat model of PA-IT.

M3 - Conference abstract in journal

SN - 0105-4538

VL - 79

SP - 276

EP - 276

JO - Allergy: European Journal of Allergy and Clinical Immunology

JF - Allergy: European Journal of Allergy and Clinical Immunology

IS - S113

M1 - 001592

T2 - European Academy of Allergy and Clinical Immunology Hybrid Congress 2024

Y2 - 31 May 2024 through 3 June 2024

ER -

A comparative dose-response study of prophylactic peanut allergy SLIT and EPIT in brown Norway rats

Abstract

Conference

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