Abstract
Laser{induced thermo therapy (LITT) is an alternative, gentle therapy of cancer. In this work a new computa-
tional model (3D space and time) of LITT is presented. Using an arbitrary small number (<20) of optical ¯bers,
multiple low energy laser light sources are applied internal to an arbitrary shaped tumor in the human liver. The
power and position of each source can be chosen arbitrary. Each source is a spherical point source emitting light
isotropically. The model consists of two, semi{coupled partial di®erential equations (PDEs) describing the light
distribution and the heat absorption in the target tissue. Since water is a dominant tissue component in both
the healthy liver and the malignant tumor the wavelength of the laser is chosen in the NIR area (1,064 nm).
This is expected to form an absorption contrast in favor of the tumor leading to high temperature and damage
of the tumor cells. The new, fast computational model presented here opens for the possibility of evaluating the
outcome of LITT by inspection of temperature ¯elds, and comparing these to measured histological damage due
to heating. This combination is promising when evaluating the result of LITT prior to the actual treatment.
Original language | English |
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Title of host publication | Therapeutic Laser Applications and Laser-Tissue Interactions IV : Proceedings of SPIE |
Volume | Vol. 7373 |
Publication date | 2009 |
DOIs | |
Publication status | Published - 2009 |
Event | Fiber Lasers VII: Technology, Systems and Applications : Therapeutic Laser Applications and Laser-Tissue Interactions - San Francisco, CA, United States Duration: 23 Jan 2010 → 28 Jan 2010 Conference number: 7 |
Conference
Conference | Fiber Lasers VII: Technology, Systems and Applications |
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Number | 7 |
Country | United States |
City | San Francisco, CA |
Period | 23/01/2010 → 28/01/2010 |
Other | SPIE volume 7580 |
Keywords
- semi{coupled PDEs
- water contrast
- LITT
- liver metastasis