TY - JOUR
T1 - 3D Biomaterial Microarrays for Regenerative Medicine
T2 - Current State-of-the-Art, Emerging Directions and Future Trends
AU - Gaharwar, Akhilesh K.
AU - Arpanaei, Ayyoob
AU - Andresen, Thomas Lars
AU - Dolatshahi-Pirouz, Alireza
PY - 2015
Y1 - 2015
N2 - Three dimensional (3D) biomaterial microarrays hold enormous promise for regenerative medicine because of their ability to accelerate the design and fabrication of biomimetic materials. Such tissue-like biomaterials can provide an appropriate microenvironment for stimulating and controlling stem cell differentiation into tissue-specifi c lineages. The use of 3D biomaterial microarrays can, if optimized correctly, result in a more than 1000-fold reduction in biomaterials and cells consumption when engineering optimal materials combinations, which makes these miniaturized systems very attractive for tissue engineering and drug screening applications.
AB - Three dimensional (3D) biomaterial microarrays hold enormous promise for regenerative medicine because of their ability to accelerate the design and fabrication of biomimetic materials. Such tissue-like biomaterials can provide an appropriate microenvironment for stimulating and controlling stem cell differentiation into tissue-specifi c lineages. The use of 3D biomaterial microarrays can, if optimized correctly, result in a more than 1000-fold reduction in biomaterials and cells consumption when engineering optimal materials combinations, which makes these miniaturized systems very attractive for tissue engineering and drug screening applications.
U2 - 10.1002/adma.201503918
DO - 10.1002/adma.201503918
M3 - Journal article
C2 - 26607415
SN - 0935-9648
VL - 28
SP - 771
EP - 781
JO - Advanced Materials
JF - Advanced Materials
IS - 4
ER -