54 Downloads (Pure)

Abstract

Current 2-D Super Resolution (SR) imaging is limited by the slice thickness determined by the elevation focus. The fixed, geometric elevation focus is often poor due to its high F-number. SR images are, thus, a summation of vessels across the elevation plane without the possibility to track scatterers in 3-D for full visualization. 3-D SR imaging has been obtained by translating the probe, but this does not remove the elevation summation. Full 3-D can be acquired using 2-D matrix probes, but the equipment is expensive, and the amount of data is excessive, when channel data are acquired over thousands of elements for minutes. This paper demonstrates that full volumetric SRI can be attained using a 62+62 channels Row-Column (RC) probe with a high frame rate and with µm precision. Data were acquired by a 3 MHz 62+62 PZT RC probe with λ/2 pitch connected to the SARUS scanner. A synthetic aperture scan sequence with 32 positive and 32 negative emissions was employed for pulse inversion (PI) imaging with an MI of 0.3. The pulse repetition frequency was 10 kHz for a 156 Hz volume rate. A PEGDA 700 g/mol based hydrogel flow-microphantom was 3-D printed by stereo-lithography. It contains a single cylindrical 200 µm diameter channel placed 3 mm from the top surface of the phantom. After a 5.8 mm long inlet, the channel bends 90º into a 7 mm long central region before bending 90º again into the 5.8 mm outlet. The flow channel was infused at 1.61 µL/s with Sonovue (Bracco) in a 1:10 dilution. The received RF signals from the 62 row elements were beamformed with PI to yield a full volume of 15 x 15 x 15 mm3 . The interpolated 3-D positions of the bubbles were estimated after local maximum detection. The reconstructed 3-D SR volume clearly shows the 200 µm channel shape with a high resolution in all three dimensions. The center line for the channel was found by fitting a line to all bubble positions, and their radial position calculated. The observed fraction of bubbles falling outside the channel was used for estimating the location precision. The precision was 16.5 µm in the y − z plane and 23.0 µm in the x − z plane. The point spread function had a size of 0.58 x 1.05 x 0.31 mm3 , so the interrogated volume was 15,700 times smaller than for normal volumetric B-mode imaging. This demonstrates that full 3-D SRI can be attained with just 62 receive channels. The SA sequence has a low MI, but attains a large measured penetration depth of 14 cm in a tissue mimicking phantom, due to the large RC probe size. The 156 Hz volume rate also makes it possible to track high velocities in 3-D in the volume.
Original languageEnglish
Title of host publicationProceedings of 2019 IEEE International Ultrasonics Symposium
Number of pages4
PublisherIEEE
Publication statusAccepted/In press - 2019
Event2019 IEEE International Ultrasonics Symposium - SEC Glasgow, Glasgow, United Kingdom
Duration: 6 Oct 20199 Oct 2019
http://attend.ieee.org/ius-2019/

Conference

Conference2019 IEEE International Ultrasonics Symposium
LocationSEC Glasgow
CountryUnited Kingdom
CityGlasgow
Period06/10/201909/10/2019
Internet address

Cite this

@inproceedings{ffee3c044cb5459b86c3885974bbd664,
title = "3-D Super Resolution Imaging using a 62+62 Elements Row-Column Array",
abstract = "Current 2-D Super Resolution (SR) imaging is limited by the slice thickness determined by the elevation focus. The fixed, geometric elevation focus is often poor due to its high F-number. SR images are, thus, a summation of vessels across the elevation plane without the possibility to track scatterers in 3-D for full visualization. 3-D SR imaging has been obtained by translating the probe, but this does not remove the elevation summation. Full 3-D can be acquired using 2-D matrix probes, but the equipment is expensive, and the amount of data is excessive, when channel data are acquired over thousands of elements for minutes. This paper demonstrates that full volumetric SRI can be attained using a 62+62 channels Row-Column (RC) probe with a high frame rate and with µm precision. Data were acquired by a 3 MHz 62+62 PZT RC probe with λ/2 pitch connected to the SARUS scanner. A synthetic aperture scan sequence with 32 positive and 32 negative emissions was employed for pulse inversion (PI) imaging with an MI of 0.3. The pulse repetition frequency was 10 kHz for a 156 Hz volume rate. A PEGDA 700 g/mol based hydrogel flow-microphantom was 3-D printed by stereo-lithography. It contains a single cylindrical 200 µm diameter channel placed 3 mm from the top surface of the phantom. After a 5.8 mm long inlet, the channel bends 90º into a 7 mm long central region before bending 90º again into the 5.8 mm outlet. The flow channel was infused at 1.61 µL/s with Sonovue (Bracco) in a 1:10 dilution. The received RF signals from the 62 row elements were beamformed with PI to yield a full volume of 15 x 15 x 15 mm3 . The interpolated 3-D positions of the bubbles were estimated after local maximum detection. The reconstructed 3-D SR volume clearly shows the 200 µm channel shape with a high resolution in all three dimensions. The center line for the channel was found by fitting a line to all bubble positions, and their radial position calculated. The observed fraction of bubbles falling outside the channel was used for estimating the location precision. The precision was 16.5 µm in the y − z plane and 23.0 µm in the x − z plane. The point spread function had a size of 0.58 x 1.05 x 0.31 mm3 , so the interrogated volume was 15,700 times smaller than for normal volumetric B-mode imaging. This demonstrates that full 3-D SRI can be attained with just 62 receive channels. The SA sequence has a low MI, but attains a large measured penetration depth of 14 cm in a tissue mimicking phantom, due to the large RC probe size. The 156 Hz volume rate also makes it possible to track high velocities in 3-D in the volume.",
author = "Jensen, {J{\o}rgen Arendt} and Mikkel Schou and Ommen, {Martin Lind} and {\O}ygard, {Sigrid Huseb{\o}} and Thomas Sams and Stuart, {Matthias Bo} and Thomsen, {Erik Vilain} and Larsen, {Niels Bent} and Christopher Beers and Tomov, {Borislav Gueorguiev}",
year = "2019",
language = "English",
booktitle = "Proceedings of 2019 IEEE International Ultrasonics Symposium",
publisher = "IEEE",
address = "United States",

}

Jensen, JA, Schou, M, Ommen, ML, Øygard, SH, Sams, T, Stuart, MB, Thomsen, EV, Larsen, NB, Beers, C & Tomov, BG 2019, 3-D Super Resolution Imaging using a 62+62 Elements Row-Column Array. in Proceedings of 2019 IEEE International Ultrasonics Symposium. IEEE, 2019 IEEE International Ultrasonics Symposium, Glasgow, United Kingdom, 06/10/2019.

3-D Super Resolution Imaging using a 62+62 Elements Row-Column Array. / Jensen, Jørgen Arendt; Schou, Mikkel; Ommen, Martin Lind; Øygard, Sigrid Husebø; Sams, Thomas; Stuart, Matthias Bo; Thomsen, Erik Vilain; Larsen, Niels Bent; Beers, Christopher; Tomov, Borislav Gueorguiev.

Proceedings of 2019 IEEE International Ultrasonics Symposium. IEEE, 2019.

Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

TY - GEN

T1 - 3-D Super Resolution Imaging using a 62+62 Elements Row-Column Array

AU - Jensen, Jørgen Arendt

AU - Schou, Mikkel

AU - Ommen, Martin Lind

AU - Øygard, Sigrid Husebø

AU - Sams, Thomas

AU - Stuart, Matthias Bo

AU - Thomsen, Erik Vilain

AU - Larsen, Niels Bent

AU - Beers, Christopher

AU - Tomov, Borislav Gueorguiev

PY - 2019

Y1 - 2019

N2 - Current 2-D Super Resolution (SR) imaging is limited by the slice thickness determined by the elevation focus. The fixed, geometric elevation focus is often poor due to its high F-number. SR images are, thus, a summation of vessels across the elevation plane without the possibility to track scatterers in 3-D for full visualization. 3-D SR imaging has been obtained by translating the probe, but this does not remove the elevation summation. Full 3-D can be acquired using 2-D matrix probes, but the equipment is expensive, and the amount of data is excessive, when channel data are acquired over thousands of elements for minutes. This paper demonstrates that full volumetric SRI can be attained using a 62+62 channels Row-Column (RC) probe with a high frame rate and with µm precision. Data were acquired by a 3 MHz 62+62 PZT RC probe with λ/2 pitch connected to the SARUS scanner. A synthetic aperture scan sequence with 32 positive and 32 negative emissions was employed for pulse inversion (PI) imaging with an MI of 0.3. The pulse repetition frequency was 10 kHz for a 156 Hz volume rate. A PEGDA 700 g/mol based hydrogel flow-microphantom was 3-D printed by stereo-lithography. It contains a single cylindrical 200 µm diameter channel placed 3 mm from the top surface of the phantom. After a 5.8 mm long inlet, the channel bends 90º into a 7 mm long central region before bending 90º again into the 5.8 mm outlet. The flow channel was infused at 1.61 µL/s with Sonovue (Bracco) in a 1:10 dilution. The received RF signals from the 62 row elements were beamformed with PI to yield a full volume of 15 x 15 x 15 mm3 . The interpolated 3-D positions of the bubbles were estimated after local maximum detection. The reconstructed 3-D SR volume clearly shows the 200 µm channel shape with a high resolution in all three dimensions. The center line for the channel was found by fitting a line to all bubble positions, and their radial position calculated. The observed fraction of bubbles falling outside the channel was used for estimating the location precision. The precision was 16.5 µm in the y − z plane and 23.0 µm in the x − z plane. The point spread function had a size of 0.58 x 1.05 x 0.31 mm3 , so the interrogated volume was 15,700 times smaller than for normal volumetric B-mode imaging. This demonstrates that full 3-D SRI can be attained with just 62 receive channels. The SA sequence has a low MI, but attains a large measured penetration depth of 14 cm in a tissue mimicking phantom, due to the large RC probe size. The 156 Hz volume rate also makes it possible to track high velocities in 3-D in the volume.

AB - Current 2-D Super Resolution (SR) imaging is limited by the slice thickness determined by the elevation focus. The fixed, geometric elevation focus is often poor due to its high F-number. SR images are, thus, a summation of vessels across the elevation plane without the possibility to track scatterers in 3-D for full visualization. 3-D SR imaging has been obtained by translating the probe, but this does not remove the elevation summation. Full 3-D can be acquired using 2-D matrix probes, but the equipment is expensive, and the amount of data is excessive, when channel data are acquired over thousands of elements for minutes. This paper demonstrates that full volumetric SRI can be attained using a 62+62 channels Row-Column (RC) probe with a high frame rate and with µm precision. Data were acquired by a 3 MHz 62+62 PZT RC probe with λ/2 pitch connected to the SARUS scanner. A synthetic aperture scan sequence with 32 positive and 32 negative emissions was employed for pulse inversion (PI) imaging with an MI of 0.3. The pulse repetition frequency was 10 kHz for a 156 Hz volume rate. A PEGDA 700 g/mol based hydrogel flow-microphantom was 3-D printed by stereo-lithography. It contains a single cylindrical 200 µm diameter channel placed 3 mm from the top surface of the phantom. After a 5.8 mm long inlet, the channel bends 90º into a 7 mm long central region before bending 90º again into the 5.8 mm outlet. The flow channel was infused at 1.61 µL/s with Sonovue (Bracco) in a 1:10 dilution. The received RF signals from the 62 row elements were beamformed with PI to yield a full volume of 15 x 15 x 15 mm3 . The interpolated 3-D positions of the bubbles were estimated after local maximum detection. The reconstructed 3-D SR volume clearly shows the 200 µm channel shape with a high resolution in all three dimensions. The center line for the channel was found by fitting a line to all bubble positions, and their radial position calculated. The observed fraction of bubbles falling outside the channel was used for estimating the location precision. The precision was 16.5 µm in the y − z plane and 23.0 µm in the x − z plane. The point spread function had a size of 0.58 x 1.05 x 0.31 mm3 , so the interrogated volume was 15,700 times smaller than for normal volumetric B-mode imaging. This demonstrates that full 3-D SRI can be attained with just 62 receive channels. The SA sequence has a low MI, but attains a large measured penetration depth of 14 cm in a tissue mimicking phantom, due to the large RC probe size. The 156 Hz volume rate also makes it possible to track high velocities in 3-D in the volume.

M3 - Article in proceedings

BT - Proceedings of 2019 IEEE International Ultrasonics Symposium

PB - IEEE

ER -

Jensen JA, Schou M, Ommen ML, Øygard SH, Sams T, Stuart MB et al. 3-D Super Resolution Imaging using a 62+62 Elements Row-Column Array. In Proceedings of 2019 IEEE International Ultrasonics Symposium. IEEE. 2019