Chemical and spectromeric methods, viz. HPLC with diode array detection, flow injection electrospray mass spectrometry and capillary electrophoresis have been used in projects on the chemotaxonomy of sepcies in the genera Aspergillus, Penicillium, Fusarium, Alternaria and Trichoderma. Chemometric methods have been used for the evaluation of the resulting chemotaxonomic data. Based on the results of the current investigations of different series in thes egenera, we have started to evaluate which secondary metabolites can be used as specific indicators of fungal growth. This is based on knowledge of the normal funga of the different foods and the chemical and spectrometric characteristics of the different secondary metabolites combined with data on possible interferences from the food matrix. While several chemical analytical methods have been developed for particular mycotoxins in foods, determination of the whole profiles of mycotoxins and other secondary metabolites in foods have rarely been attempted.We wish to detect which mycotoxins are to be expected in different foods and find specific sensitive indicators of their presence rather than developing accurate multi-mycotoxin methods with optimal reovery of all mycotoxins
|Effective start/end date||01/01/1996 → …|
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