The influence of selenium status on thyroid function before and after iodine fortification

  • Rasmussen, Lone Banke (Project Manager)

Project Details

Description

Some investigations have shown that selenium deficiency, like iodine deficiency, can be risk factor for goiter and can influence thyroid function. The aim of the project is to study the influence of selenium status on thyroid function and the relation between selenium status, iodine status and thyroid hormones.

Blood samples have been collected, the thyroid volume and the iodine intake has been measured in the DanThyr study both before and after introduction of iodine fortification. In this study the blood samples will be analysed for selenium.

Thyroid hormones and thyroid volume will be compared between 4 groups: 1. High iodine intake, high selenium intake, 2. High iodine intake, low selenium intake, 3. Low iodine intake, high selenium intake, 4. Low iodine intake, low selenium intake. Furthermore, multiple linear regression models with various parameters for thyroid function as the dependent variabel and selenium and iodine status e.g. as independent variables will be performed.
StatusFinished
Effective start/end date01/07/200601/01/2008