Site specific recombination system of lactococcal phage TP901-1

TP901-1 is a temperate bacteriophage using Lactococcus lactis subsp. cremoris 3107 as host. During infection the phage genome can integrate site-specifically into the bacterial chromosome by recombination between the attachment sites attB and attP located on the bacterial and the phage genomes, respectively. In this project the phage encoded elements involved in integration are analysed. The detailed knowledge of the molecular components of the integration-excision system from the temperate bacteriophage TP901-1 shall encourage an integrated vision of the phage-host interactions in these processes and the physiological control exerted.