Separation of Macromolecules by Photonic Crystal Defect Chromotography

  • Hassager, Ole (Project Manager)
  • Mortensen, N. Asger (Project Participant)
  • Yvind, Kresten (Project Participant)
  • Teraoka, Iwao (Project Participant)
  • Javier Alvarez, Nicolas (Project Participant)
  • Jeppesen, Claus (Project Participant)

Project Details

Description

This project introduces a new and revolutionary way to separate macromolecules. The principle is to use light to selectively retain some molecules over others depending on their differential interaction with optical fields. We call the method Photonic Crystal Defects Chromatography (PCDC), as it combines photonic crystals with artificial defects and a flow channel that constitutes a “column” of conventional liquid chromatography. The method will be useful both for biopolymers (like DNA and proteins) and synthetic polymers. It could potentially have profound implications for several biological and biomedical applications such as proteomics and cancer diagnostics, in which fast and high resolution separation of nucleic acids and proteins from a complex biological fluid is a key aspect.
StatusFinished
Effective start/end date01/08/201101/08/2013

Research Output

  • 1 Conference abstract for conference

The continuous separation of molecules on the basis of their polarizability using optical electric fields

Javier Alvarez, N., Jeppesen, C., Yvind, K., Mortensen, N. A., Teraoka, I. & Hassager, O., 2012. 1 p.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
File

Activities

  • 1 Conference presentations

The continuous separation of molecules on the basis of their polarizability using optical electric fields

Nicolas Javier Alvarez (Speaker)

19 Jun 2012

Activity: Talks and presentationsConference presentations

File