Micro flow systems for isolation, manipulation and analysis of foetal cells in blood

  • Blankenstein, Gert (Project Manager)
  • Hougaard, Charlotte (Project Participant)

    Project Details


    Content of this project is to develop a system for separation and analysis of foetal cells in whole blood by using and integrated automated micro flow system. Sorting of foetal cells in maternal blood provides a non-invasive alternative to prenatal diagnostic procedures, such as amniocentesis of chlorionic villus sampling. In this context a magnetic separation system, developed at MIC, could be a tool for rare event isolation of foetal cells. Separation of foetal cells from the maternal blood is based on specific surface markers and/or physical specification, e.g. cell volume and cell size. The project has started in collaboration with Chromosomal Laboratory at the Rigshospital. Experiments with maternal blood samples are under preparation and will be carried out during the next couple of months.
    Effective start/end date01/01/1996 → …