HOPE

Description

13 used and potential endocrine disruptive pesticides will be analysed for mechanistic effects both in QSAR, in a battery of six different vitro tests, in an ex vivo human placenta model and finally in a short-term animal study. Mixtures of selected pesticides will be studies in the different tests as well.

Based on this study knowledge on the applicability of the different in vitro studies as well as the QSAR approach will be evaluated.
StatusFinished
Effective start/end date01/09/200930/06/2012