Effects of Xenohormones on Crustaceans

Project Details

Description

The aim of the project is to develop a fast and easy method to identify chemicals, which act as hormones in humans and wild life.

The increasing incidence of some cancer types, damage to reproductive systems and developmental problems of this system of humans and wildlife has caused concern about some industrial compounds used in high quantities, which can mimic the natural hormones and actsas such. Crustaceans posses the same hormones as many other animal groups - oestrogen, testerone and progesterone - among others have been identified, and it seems likely that the hormones act in the sameway in Crustaceans as in mammals. In this project is used the small (1 mm) copepod, Acartia tonsa, as a test animal. It is a very common planktonic organism in European coastal waters and as such of great ecological importance. It is easily cultured and handled in the laboratory.

Suspected oestrogen such as alkylphenoles, alkylphenole ethoxylates, bisphenol A and plastic softeners has been investigated together with the positive control oestrogen and some negative controls to find parameters which will show or at least indicate if the compounds act as hormones.
Life cycle tests with Acartia is performed, and focus is directed against different parts of the lifecycle.
Acronym43
StatusFinished
Effective start/end date01/10/199631/12/2000