The metabolism of n-3 fatty acids from fish oil has been studied for many years in various aspects comprising absorption, tissue deposition and influence on blood lipids. A comparison of the absorption of microencapsulated fish oil with a conventional oil showed the same deposition of fatty acids in rat tissues, indicating a full availability of the microencapsulated product. This is of special importance with respect to the use in infant formulas, as it is known that fish oil fatty acids are beneficial for the development of nervous tissue and hereby the retina. In a collaboration project with Dept. Human Nutrition, RVAU, we have studied the influence of dietary EPA and DHA on visual acuity in infants, taking the deposition of these n-3 fatty acids in red blood cells as a measure of availability. Term infants were given formulas with and without fish oil fatty acids and compared with breast fed babies. The visual acuity was found significantly lower after 4 months, when DHA was omitted from the formula.
|Effective start/end date||18/06/1992 → 31/07/1996|