DNA supercoiling and Nucleoid structure in E. coli

    Project Details


    This project is a collaboration with Dr. Conrad Woldringh, Institute for Molecular Cell Biology, Biocentrum, University of Amsterdam, Holland. Using strains with tunable expression of the topoisomerase genes, we modulate the level of DNA supercoiling and study the effects hereof on compaction and expansion of the bacterial nucleoid.
    Effective start/end date01/01/199301/01/9999