Combinatorial and Bioorganic Synthesis

The project "Combinatorial and Bioorganic Synthesis" is a collaborative project between the combinatorial and solid-phase synthesis group at the DTU and Dr. Mikael Bols group at Aarhus University. The project is financed by the Danish Research Council.
The project focus is on the application of combinatorial chemical techniques for approaching or solving scientific problems of chemical, medicinal or biological relevance. The specific projects embrace
a) "Glycobiotics" which include synthesis of oligosaccharide mimetic and construction of combinatorial libraries of glycobiotics.
b) "Approaching natural product synthesis by combinatorial chemistry" which include convergent synthesis of Actinomycin D analogues, the implementation of double-combinatorial chemistry, and combinatorial synthesis of balanol analogues.