The project focusses on the synthetic potential of selectively activated aldonolactones. These can be easily accessed in few steps from aldonolactones, avoiding any protection/deprotection group strategy. In this part of the project the main emphasis will be on stereocontrolled formation of carbon-carbon bonds to elucidate methodologies for the synthesis of carbohydrate mimics in a broader sense. Thus, pharmacologically active chiral compounds may be prepared.
|Effective start/end date||01/01/1998 → …|