• Kemitorvet, 204, 249

    2800 Kgs. Lyngby

    Denmark

20122022
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Research Output 2012 2018

2018
267 Downloads (Pure)

CD103+ CD11b+ mucosal classical dendritic cells initiate long-term switched antibody responses to flagellin

Flores-Langarica, A., Müller Luda, K., Persson, E. K., Cook, C. N., Bobat, S., Marshall, J. L., Dahlgren, M. W., Hägerbrand, K., Toellner, K. M., Goodall, M. D., Withers, D. R., Henderson, I. R., Johansson Lindbom, B., Cunningham, A. F. & Agace, W. W., 1 May 2018, In : Mucosal Immunology. 11, 3, p. 681-692

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Characterization of Murine Intestinal Mesenchymal Stromal Cells

Pærregaard, S. I., Schussek, S., Jendholm, J., Niss, K., Vandamme, J., Sitnik, K., Svensson-Frej, M. & Agace, W. W., 2018.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

109 Downloads (Pure)

Intestinal CD103+CD11b+ cDC2 conventional dendritic cells are required for primary CD4+ T and B cell responses to soluble flagellin

Flores-Langarica, A., Cook, C., Luda, K. M., Persson, E. K., Marshall, J. L., Beristain-Covarrubias, N., Yam-Puc, J. C., Dahlgren, M., Persson, J. J., Uematsu, S., Akira, S., Henderson, I. R., Lindbom, B. J., Agace, W. & Cunningham, A. F., 2018, In : Frontiers in Immunology. 9, 9 p., 2409.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Retinoic Acid Signaling in Stromal Cells Regulates Intestinal Lymphoid Tissue Stromal Development

von Burg, N. C., Sitnik, K. M., Vandamme, J., Wu, N. Y. H., Kotarsky, K., Ludewig, B. & Agace, W. W., 2018.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

1 Downloads (Pure)

Retinoic Acid Signaling in Thymic Epithelial Cells Regulates Thymopoiesis

Wendland, K., Niss, K., Kotarsky, K., Wu, N. Y. H., White, A. J., Jendholm, J., Rivollier, A., Izarzugaza, J. M. G., Brunak, S., Holländer, G. A., Anderson, G., Sitnik, K. M. & Agace, W. W., 2018, In : Journal of Immunology. 200, 11, 13 p., ji1800418.

Research output: Contribution to journalJournal articleResearchpeer-review

173 Downloads (Pure)

The role of TLR3/TRIF and type I IFN signaling in the migration of intestinal DC subsets in response to poly(I:C)

Garcia Lopez, A., Bekiaris, V., Müller-Luda, K., Hütter, J., Holzmann, B., Agace, W. & Lahl, K., 2018, In : European Journal of Immunology. 48, S1, p. 150-150 P–227.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Open Access
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2017

Characterization of leukocytes in distinct human intestinal compartments

Fenton, T., Jorgensen, P., Riis, L. B., Jacobsen, H. L., Nielsen, O. H. & Agace, W. W., 2017, In : Scandinavian Journal of Immunology. 86, 4, p. 298-299 2 p., A-31498.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

302 Downloads (Pure)

Different populations of CD11b+ dendritic cells drive Th2 responses in the small intestine and colon

Mayer, J. U., Demiri, M., Agace, W. W., MacDonald, A. S., Svensson Frej, M. & Milling, S. W., 2017, In : Nature Communications. 8, 15820.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Distinct DC subsets regulate adaptive Th1 and 2 responses during Trichuris muris infection

Demiri, M., Müller-Luda, K., Agace, W. W. & Svensson Frej, M., 2017, In : Parasite Immunology. 39, 10, e12458.

Research output: Contribution to journalJournal articleResearchpeer-review

98 Downloads (Pure)

Diversity and functions of intestinal mononuclear phagocytes

Joeris, T., Müller-Luda, K., Agace, W. W. & Mowat, A. M., 2017, In : Mucosal Immunology. 10, 4, p. 845-864

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
144 Downloads (Pure)

Eosinophils are key regulators of perivascular adipose tissue and vascular functionality

Withers, S. B., Forman, R., Meza-Perez, S., Sorobetea, D., Sitnik, K., Hopwood, T., Lawrence, C. B., Agace, W. W., Else, K. J., Heagerty, A. M., Svensson Frej, M. & Cruickshank, S. M., 2017, In : Scientific Reports. 7, 12 p., 44571.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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60 Downloads (Pure)

GP2 is selectively expressed by small intestinal CD103+CD11b+ cDC

Müller-Luda, K., Ahmadi, F., Ohno, H., Kotarsky, K. & Agace, W. W., 2017.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
File
138 Downloads (Pure)

Irf4-dependent CD103+CD11b+ dendritic cells and the intestinal microbiome regulate monocyte and macrophage activation and intestinal peristalsis in postoperative ileus

Pohl, J. M., Gutweiler, S., Thiebes, S., Volke, J. K., Klein-Hitpass, L., Zwanziger, D., Gunzer, M., Jung, S., Agace, W. W., Kurts, C. & Engel, D. R., 2017, In : Gut. 66, 12, p. 2110–2120

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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189 Downloads (Pure)

Regionalized Development and Maintenance of the Intestinal Adaptive Immune Landscape

Agace, W. W. & McCoy, K. D., 2017, In : Immunity. 46, 4, p. 532-548 17 p.

Research output: Contribution to journalReviewResearchpeer-review

Open Access
File
45 Downloads (Pure)

The role of retinoic acid signaling in thymic function

Wendland, K., Sitnik, K., Kotarsky, K., Anderson, G. & Agace, W. W., 2017.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
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2016

A reduced population of CD103+ CD11b+ dendritic cells has a limited impact on oral Salmonella infection

Fernandez-Santoscoy, M., Wenzel, U. A., Persson, E., Yrlid, U., Agace, W. W. & Wick, M. J., 2016, In : Immunology Letters. 176, p. 72-80 9 p.

Research output: Contribution to journalJournal articleResearchpeer-review

271 Downloads (Pure)

Context-Dependent Development of Lymphoid Stroma from Adult CD34+ Adventitial Progenitors

Sitnik, K. M., Wendland, K., Weishaupt, H., Uronen-Hansson, H., White, A. J., Anderson, G., Kotarsky, K. & Agace, W. W., 2016, In : Cell Reports. 14, 10, p. 2375-2388 14 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Evidence for a dual function of monocyte-derived mononuclear phagocytes during chronic intestinal inflammation

Rivollier, A. M. C., Pool, L., Frising, U., Danilova, E. & Agace, W. W., 2016. 1 p.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

173 Downloads (Pure)

IL-18Rα-deficient CD4+T cells induce intestinal inflammation in the CD45RBhitransfer model of colitis despite impaired innate responsiveness

Holmkvist, P., Pool, L., Hägerbrand, K., Agace, W. W. & Rivollier, A. M. C., 2016, In : European Journal of Immunology. 46, 6, p. 1371-1382

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
34 Downloads (Pure)

IRF8 dependent classical dendritic cells are essential for intestinal T cell homeostasis

Luda, K., Joeris, T., Persson, E. K., Rivollier, A. M. C., Demiri, M., Sitnik, K. M., Pool, L., Holm, J. B., Melo-Gonzalez, F., Richter, L., Lambrecht, B. N., Kristiansen, K., Travis, M. A., Svensson-Frej, M., Kotarsky, K. & Agace, W. W., 2016, In : European Journal of Immunology. 46, Suppl. 1, p. 946-946

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Open Access
File
32 Downloads (Pure)

IRF8-dependent DCs play a key role in the regulation of CD8 T cell responses to epithelialderived antigen in the steady state but not in inflammation

Joeris, T., Gomez-Casado, C., Holmkvist, P., Luda, K., Tavernier, S., Lambrecht, B. N. & Agace, W. W., 2016, In : European Journal of Immunology. 46, Suppl. 1, p. 788-788

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Open Access
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IRF8-dependent DCs play a key role in the regulation of CD8 T cell responses to epithelial-derived antigen in the steady state but not in inflammation

Joeris, T., Casado, G. C., Holmkvist, P., Luda, K., Tavernier, S., Lambrecht, B. N. & Agace, W. W., 2016, In : European Journal of Immunology. 46, S1, p. 787-787 1 p.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

IRF8 Transcription Factor Controls Survival and Function of Terminally Differentiated Conventional and Plasmacytoid Dendritic Cells, Respectively

Sichien, D., Scott, C. L., Martens, L., Vanderkerken, M., Van Gassen, S., Plantinga, M., Joeris, T., De Prijck, S., Vanhoutte, L., Vanheerswynghels, M., Van Isterdael, G., Toussaint, W., Madeira, F. B., Vergote, K., Agace, W. W., Clausen, B. E., Hammad, H., Dalod, M., Saeys, Y., Lambrecht, B. N. & 1 others, Guilliams, M., 2016, In : Immunity. 45, 3, p. 626-640 15 p.

Research output: Contribution to journalJournal articleResearchpeer-review

103 Downloads (Pure)

IRF8 Transcription-Factor-Dependent Classical Dendritic Cells Are Essential for Intestinal T Cell Homeostasis

Luda, K. M., Joeris, T., Persson, E. K., Rivollier, A. M. C., Demiri, M., Sitnik, K. M., Pool, L., Holm, J. B., Melo-Gonzalez, F., Richter, L., Lambrecht, B. N., Kristiansen, K., Travis, M. A., Svensson-Frej, M., Kotarsky, K. & Agace, W. W., 2016, In : Immunity. 44, 4, p. 860-874 15 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Long-term persistence of human donor alveolar macrophages in lung transplant recipients

Eguíluz-Gracia, I., Schultz, H. H. L., Sikkeland, L. I. B., Danilova, E., Holm, A. M., Pronk, C. J. H., Agace, W. W., Iversen, M., Andersen, C., Jahnsen, F. L. & Baekkevold, E. S., 2016, In : Thorax. 71, 11, p. 1006-1011 6 p.

Research output: Contribution to journalJournal articleResearchpeer-review

195 Downloads (Pure)

Macrophage and dendritic cell subsets in IBD: ALDH+ cells are reduced in colon tissue of patients with ulcerative colitis regardless of inflammation

Magnusson, M. K., Brynjólfsson, S. F., Dige, A., Uronen-Hansson, H., Börjesson, L. G., Bengtsson, J. L., Gudjonsson, S., Öhman, L., Agnholt, J., Sjövall, H., Agace, W. W. & Wick, M. J., 2016, In : Mucosal Immunology. 9, 1, p. 171-182 12 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Retinoic acid signalling is required for the pathogenicity of effector CD4+ T cells during the development of intestinal inflammation

Rivollier, A. M. C., Pool, L., Frising, U., Wendland, K. & Agace, W. W., 2016. 1 p.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

2015
186 Downloads (Pure)

A major population of mucosal memory CD4+ T cells, coexpressing IL-18Rα and DR3, display innate lymphocyte functionality

Holmkvist, P., Roepstorff, K., Uronen-Hansson, H., Sanden, C., Gudjonsson, S., Patschan, O., Grip, O., Marsal, J., Schmidtchen, A., Hornum, L., Erjefalt, J. S., Hakansson, K. & Agace, W. W., 2015, In : Mucosal Immunology. 8, 3, p. 545-558 14 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
81 Downloads (Pure)

CCR2+CD103 intestinal dendritic cells develop from DC-committed precursors and induce interleukin-17 production by T cells

Scott, C. L., Bain, C. C., Wright, P. B., Sichien, D., Kotarsky, K., Persson, E. K., Luda, K., Guilliams, M., Lambrecht, B. N., Agace, W. W., Milling, S. WF. & Mowat, A. M., 2015, In : Mucosal Immunology. 8, 2, p. 327-339

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
File
39 Downloads (Pure)

CCR9 Is Not Required for the Homing of Pro-inflammatory Effector T cells, but Is Crucial for Recruitment and Expansion of FoxP3+ CD8+ Tregs in the Small Intestine

Gomez-Casado, C., Joeris, T., Holmkvist, P. & Agace, W. W., 2015. 1 p.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
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CCRL1/ACKR4 is expressed in key thymic microenvironments but is dispensable for T lymphopoiesis at steady state in adult mice

Lucas, B., White, A. J., Ulvmar, M. H., Nibbs, R. J. B., Sitnik, K. M., Agace, W. W., Jenkinson, W. E., Anderson, G. & Rot, A., 2015, In : European Journal of Immunology. 45, 2, p. 574-583

Research output: Contribution to journalJournal articleResearchpeer-review

58 Downloads (Pure)

Context dependent development of lymphoid organ mesenchymal subsets fromBP3-Gp38+ PDGFRβ++CD34+ vascular adventitial precursors

Sitnik, K. M., Wendland, K., Weishaupt, H., Uronen-Hansson, H., Anderson, G., Kotarsky, K. & Agace, W. W., 2015. 1 p.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
File
36 Downloads (Pure)

Involvement of IRF4 dependent dendritic cells in T cell dependent colitis

Pool, L., Rivollier, A. M. C. & Agace, W. W., 2015. 1 p.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
File
57 Downloads (Pure)

Involvement of IRF4 dependent dendritic cells in T cell dependent colitis

Pool, L., Rivollier, A. M. C. & Agace, W. W., 2015. 1 p.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
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Involvement of neurons and retinoic acid in lymphatic development: new insights in increased nuchal translucency

Burger, N. B., Stuurman, K. E., Kok, E., Konijn, T., Schooneman, D., Niederreither, K., Coles, M., Agace, W. W., Christoffels, V. M., Mebius, R. E., van de Pavert, S. A. & Bekker, M. N., 2015, In : Prenatal Diagnosis. 34, 13, p. 1312-1319

Research output: Contribution to journalJournal articleResearchpeer-review

40 Downloads (Pure)

IRF8-dependent DCs Play a Key Role in the Regulation of CD8 T Cell Responses to Epithelial-derived Antigen in the Steady State but not in Inflammation

Joeris, T., Gomez-Casado, C., Holmkvist, P., Agace, W. W. & Luda, K., 2015. 1 p.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
File
61 Downloads (Pure)

Lymph-borne CD8α+ dendritic cells are uniquely able to cross-prime CD8+ T cells with antigen acquired from intestinal epithelial cells

Cerovic, V., Houston, S. A., Westlund, J., Utriainen, L., Davison, E. S., Scott, C. L., Bain, C. C., Joeris, T., Agace, W. W., Kroczek, R. A., Mowat, A. M., Yrlid, U. & Milling, S. W. F., 2015, In : Mucosal Immunology. 8, 1, p. 38-48 11 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Open Access
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Lymphocyte Trafficking to Mucosal Tissues

Mikhak, Z., Agace, W. W. & Luster, A. D., 2015, Mucosal Immunology. Mestecky, J., Strober, W., Russell, M. W., Cheroutre, H., Lambrecht, B. N. & Kelsall, B. L. (eds.). 4 ed. Elsevier, Vol. 1. p. 805-830

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

MyD88 Signaling Regulates Steady-State Migration of Intestinal CD103+ Dendritic Cells Independently of TNF-α and the Gut Microbiota

Hägerbrand, K., Westlund, J., Yrlid, U., Agace, W. W. & Lindbom, B. J., 2015, In : Journal of Immunology. 195, 6, p. 2888-2899 12 p.

Research output: Contribution to journalJournal articleResearchpeer-review

Physiological Role of TNF in MucosalImmunology: Regulation of Macrophage/Dendritic Cell Function

Rivollier, A. M. C., Marsal, J. & Agace, W. W., 2015, Anti-Tumor Necrosis Factor Therapy in Inflammatory Bowel Disease. Rogler, G., Herfarth, H., Hibi, T. & Nielsen, O. H. (eds.). Karger, Vol. 34. p. 9-26 (Frontiers of Gastrointestinal Research).

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

84 Downloads (Pure)

Retinoic acid signalling in thymocytes regulates T cell development

Wendland, K., Sitnik, K. M., Kotarsky, K., White, A. J., Anderson, G. & Agace, W. W., 2015. 1 p.

Research output: Contribution to conferencePosterResearchpeer-review

Open Access
File
47 Downloads (Pure)

Retinoic acid signalling in thymocytes regulates T cell development

Wendland, K., Sitnik, K. M., Kotarsky, K., White, A. J., Anderson, G. & Agace, W. W., 2015. 1 p.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
File
93 Downloads (Pure)

Retinoic acid signalling is required for the efficient differentiation of CD4+ T cells into pathogenic effector cells during the development of intestinal inflammation

Rivollier, A. M. C., Pool, L., Frising, U., Wendland, K. & Agace, W. W., 2015. 1 p.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
File
39 Downloads (Pure)

Thymic and lymph node mesenchymal subsets can be derived from PDGFRα/β+Gp38+CD34+ICAM1- vascular adventitial precursors

Sitnik, K. M., Wendland, K., Weishaupt, H., Uronen-Hansson, H., Jenkinson, W., Anderson, G., Kotarsky, K. & Agace, W. W., 2015. 1 p.

Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

Open Access
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2014

CD14 hi HLA-DR dim macrophages, with a resemblance to classical blood monocytes, dominate inflamed mucosa in Crohn’s disease

Thiesen, S., Janciauskiene, S., Uronen-Hansson, H., Agace, W. W., Hogerkorp, C-M., Spee, P., Hakansson, K. & Hakansson, K., 2014, In : Journal of Leukocyte Biology. 95, 3, p. 531-541

Research output: Contribution to journalJournal articleResearchpeer-review

Dendritic cell subsets in mucosal immune responses

Agace, W. W., 2014, In : Immunology. 143, SI , p. 21 1 p., 148.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Dendritic cell subsets in the regulation of intestinal immune responses

Luda, K., Persson, E., Joeris, T., Lambrecht, B. & Agace, W. W., 2014, In : Immunology. 143, SI, p. 6 1 p., S5.1.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

Intestinal dendritic cells in the regulation of mucosal immunity.

Bekiaris, V., Persson, E. K. & Agace, W. W., 2014, In : Immunological Reviews. 260, 1, p. 86-101 16 p.

Research output: Contribution to journalJournal articleResearchpeer-review

IRF4-Dependent Dendritic Cells Regulate CD4(+) T Cell Responses to Soluble Oral Antigens

Persson, E., Luda, K., Mowat, A. M., Kotarsky, K. & Agace, W. W., 2014, In : Scandinavian Journal of Immunology. 79, 6, p. 447 1 p.

Research output: Contribution to journalConference abstract in journalResearchpeer-review

IRF4-dependent gut dendritic cells control the mucosal IgA response to flagellin

Flores-Langarica, A., Persson, E. K., Luda, K., Cook, C., Bobat, S., Agace, W. W. & Cunningham, A. F., 2014, In : Immunology. 143, SI , p. 59 1 p., 247.

Research output: Contribution to journalConference abstract in journalResearchpeer-review