Research output per year
Research output per year
Personal profile
Profile
Summary
I have been working throughout the last 11 years in the field of microfluidic research and development for life science applications. This included extended activities in the field of design analysis, prototype design, fabrication and test as well as project generation management and team management. Typical areas of applications have been the development of diagnostic devices for drug detection in saliva, cultivation of stem cells, in vitro fertilization and cell-based assays in the field of cancer research. But also large-scale fluidic simulations of high velocity turbulent flow in maritime devices have been part of my work in function as Senior Consultant at the Danish Technological Institute.At the Department for Chemical and Biochemical Engineering I am responsible for the microfluidic activities of the PROCESS group. We are currently developing microbioreactors for biotechnological and pharmaceutical processes.
Other information
Language Skills:
German (mother tongue)
English
Danish
French
Russian (basic)
German (mother tongue)
English
Danish
French
Russian (basic)
Education/Academic qualification
Chemical Engineer, MSc, Technische Universität Berlin
15 Oct 1987 → 31 Jul 1995
Award Date: 31 Jul 1995
External positions
Senior Consultant / Teamleader / Program Leader
1 Jan 2003 → 28 Feb 2011Senior Researcher / CEO, CelTor Biosystems, Inc.
1 Apr 2000 → 31 Dec 2002Keywords
- User defined:
- Microfluidics, Microbioreactors, in vitro cell investigations, Computational Fluid Dynamics, Simulation
Fingerprint
Dive into the research topics where Ulrich Krühne is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
Network
Recent external collaboration on country level. Dive into details by clicking on the dots or
Research output
-
Benefits and Challenges of a Virtual Laboratory in Chemical and Biochemical Engineering: Students’ Experiences in Fermentation
Caño de las Heras, S., Kensington-Miller, B., Young, B., Gonzalez, V., Krühne, U., Mansouri, S. S. & Baroutian, S., 2021, (Accepted/In press) In : Journal of Chemical Education.Research output: Contribution to journal › Journal article › Research › peer-review
-
Towards the Development of Digital Twins for the Bio-manufacturing Industry
L. Gargalo, C., Caño de Las Heras, S., Jones, M. N., Udugama, I., Mansouri, S. S., Krühne, U. & Gernaey, K. V., 2021, (Accepted/In press) Advances in Biochemical Engineering/Biotechnology. Berlin, Heidelberg: Springer, (Advances in Biochemical Engineering/Biotechnology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
-
A Disposable Passive Microfluidic Device for Cell Culturing
Guzzi, F., Candeloro, P., Coluccio, M. L., Cristiani, C. M., Parrotta, E. I., Scaramuzzino, L., Scalise, S., Dattola, E., D’Attimo, M. A., Cuda, G., Lamanna, E., Passacatini, L. C., Carbone, E., Krühne, U., Di Fabrizio, E. & Perozziello, G., 2020, In : Biosensors. 10, 3, 14 p., 18.Research output: Contribution to journal › Journal article › Research › peer-review
Open AccessFile -
An Education l Bioprocess Simulator (BioVL): Introduction of Disturbances
Caño de Las Heras, S., L. Gargalo, C., A. Udugama, I., Gernaey, K. V. & Krühne, U., 2020. 2 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
Open AccessFile5 Downloads (Pure) -
An E-learning Bot for Bioprocess Systems Engineering
Caño de Las Heras, S., Jones, M. N., Gernaey, K. V., Krühne, U. & Mansouri, S. S., 2020, Proceedings of the 30th European Symposium on Computer Aided Process Engineering (ESCAPE30). Pierucci, S., Manenti, F., Bozzano, G. & Manca, D. (eds.). Elsevier, p. 2023-2028Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research › peer-review
Projects
-
Digital twins of pilot-scale biopharma production processes
Muldbak, M., Gernaey, K. V., Loureiro da Costa Lira Gargalo, C. & Krühne, U.
01/12/2020 → 30/11/2023
Project: PhD
-
Spectroscopy and mathematical models as pharma manufacturing Process Analytical Technology tools
Jul-Jørgensen, I., Gernaey, K. V., Krühne, U., Hundahl, C. A. & Oskolkova, M. M. Z.
01/10/2020 → 30/09/2023
Project: PhD
-
Evaluation of single-pass tangential flow filtration (SPTFF) to increase productivity in protein purification processes
Kaiser, J., Krühne, U., Pinelo, M. & Krarup, J.
01/06/2019 → 31/05/2022
Project: PhD
-
Development of electrochemical metabolite sensors to monitor stress responses in-situ in large bioreactors
Hasanzadeh, A., Gernaey, K. V., Kilstrup, M. & Krühne, U.
01/01/2019 → 31/12/2021
Project: PhD
-
Development of a Virtual Educational Bioprocess Plant
Caño de Las Heras, S., Krühne, U., Mansouri, S. S. & Loureiro da Costa Lira Gargalo, C.
Technical University of Denmark
01/09/2018 → 31/08/2021
Project: PhD
Activities
- 8 Conference presentations
-
An Educational Bioprocess Simulator (BioVL): Introduction of Disturbances
Simoneta Caño de Las Heras (Speaker), Carina Loureiro da Costa Lira Gargalo (Other), Isuru Sampath Bandara Abeykoon Udugama (Other), Krist V. Gernaey (Other) & Ulrich Krühne (Other)
18 Nov 2020Activity: Talks and presentations › Conference presentations
File -
Towards the use of multi-relational data mining (MRDM) in bioprocess models
Simoneta Caño de Las Heras (Speaker), Carina Loureiro da Costa Lira Gargalo (Other), Isuru Sampath Bandara Abeykoon Udugama (Other), Krist V. Gernaey (Other) & Ulrich Krühne (Other)
17 Nov 2020Activity: Talks and presentations › Conference presentations
File -
Topology optimization as a tool for designing microbioreactors
Ines Pereira Rosinha Grundtvig (Speaker), Anders Egede Daugaard (Other), John Woodley (Other) & Ulrich Krühne (Other)
1 Oct 2017 → 5 Oct 2017Activity: Talks and presentations › Conference presentations
File -
Design of a gas-inducing impeller using Computational Fluid Dynamics
Ines Pereira Rosinha Grundtvig (Guest lecturer), Tim Hybschmann (Other), Krist V. Gernaey (Other), Tore C. Svendsen (Other) & Ulrich Krühne (Other)
1 Oct 2017 → 5 Oct 2017Activity: Talks and presentations › Conference presentations
File -
A Biocatalytic Microreactor – Dynamic CFD Modelling and Experimental Analysis
Ulrich Krühne (Lecturer)
27 Sep 2016Activity: Talks and presentations › Conference presentations
File
Prizes
-
Best Contributed Paper Award
Caño de Las Heras, Simoneta (Recipient), Mansouri, Seyed Soheil (Recipient), Helle Rootzén (Recipient), Charlotte Lærke Weitze (Recipient), Gernaey, Krist V. (Recipient), Krühne, Ulrich (Recipient) & Stefano Cignitti (Recipient), 5 Jul 2018
Prize: Prizes, scholarships, distinctions